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Postdoctoral Position – RNA Biology & Cancer
Dr. Olga Anczuków, PhD, Assistant Professor
The Jackson Laboratory for Genomic Medicine, CT
About the position: We are looking for talented postdoctoral candidates to investigate how misregulation of alternative RNA splicing contributes to human disease, with a specific focus on cancer. The positions are fully funded through two NIH grants, and awaiting the proper, enthusiastic applicant.
Our research goals are to: i) define the molecular pathways that regulate splicing factors in normal and cancer cells, as well as during cell differentiation; ii) uncover causal splicing alterations in breast tumors; and iii) identify splicing factors and spliced isoforms which could be used as biomarkers to predict disease progression or drug-response, or as targets for RNA-based therapeutics. Our research uses 3D cell culture models, mouse models including patient-derived xenograft, as well as large clinical datasets, and leverages cutting-edge approaches such as RNA-targeting CRISPR, short- and long-read RNA-sequencing, and single-cell approaches, to decipher the role of spliced isoforms and their regulators.
Our research group, consisting of a postdoctoral associate, two graduate students, and two research associates, is diverse and collaborative. We seek to produce top notch science and foster the development of outstanding, independent scientists through nurturing mentorship and interdisciplinary, collaborative efforts. We have close collaboration with members of the JAX NCI-designated Cancer Center and the Nathan Shock Excellence of Research on Aging Center. For more, visit the Anczuków Lab online.
Resident Advisor– Summer Student Program
The Summer Student Program is a signature education program of The Jackson Laboratory. The Resident Advisor implements the residential life program within the JAX Summer Student Program including day-to-day logistics and recreational activities. With oversight and guidance from the Program Director of the Summer Student Program, the Resident Advisor fosters programmatic harmony through communication and problem-solving, and ensures student safety through awareness and compliance with JAX policies. By organizing residential activities, the RA generates excitement, builds community, and fosters inclusion and a sense of fun and team spirit throughout the program.
The Residential Advisors share leadership of a cohort of approximately 10 undergraduate students ranging in age from 18-21. These participants are selected through a highly competitive application process that draws nearly 1,000 applications from around the US. Selected students exhibit personal qualities including curiosity and a passion for science, resilience and problem solving, personal maturity, and teamwork. This student body is highly diverse, and includes individuals from many races, ethnicities, socioeconomic backgrounds, genders, abilities, and beliefs.
Students in the JAX Summer Student Program are housed in apartment or suite-style housing nearby at either the University of St. Joseph or the University of Hartford.
Genomics Education Fellow
Location: Farmington, CT or Bar Harbor, ME
The Genomics Education Fellow will design, develop and teach in courses and educational programs focused on the genomics and genetics of cancer and the computational techniques used to study it. Reporting to the Director of Education, the fellow will focus on curriculum development, teaching and educational programming using evidence-based practices and instructional design principles. The fellow will be a critical member of the Genomic Education team and will work with other Education program directors and content developers to create engaging educational experiences, both in person and digitally, to expand and enhance education programs that reflect JAX’s mission to become a center of excellence in cancer genetics and genomics education. The fellow will interact with and design content for a range of learners, including high school and undergraduate faculty, undergraduate and graduate students. The Genomics Education Fellow will be a subject matter expert and experienced instructor, who will assist in the preparation, execution and evaluation of grant funded research education programs. This is a two-year training fellowship position. The fellow will receive mentorship and career advising to support their development as an educator and help them succeed in a variety of careers with an education focus. This is a full-time position within JAX Genomic Education and offers a competitive salary and benefits package.
APPLICATION REQUIREMENT:Please submit a cover letter of interest along with your resume. Applications without a cover letter will not be considered.
Research Assistant I
The Ucar laboratory at The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking talented individuals experienced in computing and bioinformatics. The focus of the Ucar laboratory is to understand how epigenomes of human immune cells change with age and diseases including COVID-19. More information can be found at: https://www.ucarlab.com/
We are seeking highly-motivated individuals who have prior experience with computational methods focused on NGS data analysis, and some previous exposure to genomics and genetics.
The Kaczorowski Lab at The Jackson Laboratory is seeking an Associate Research Scientist to support our ongoing research program and to develop new research projects. Our group primarily focuses on mechanisms of learning and memory, as well as genetic diseases of aging (Alzheimer’s and related dementias). The successful candidate will continue and extend studies of the molecular signatures that underlie learning and memory, and disease-related pathological changes in translational models of Alzheimer’s disease. The applicant must be a team player with exceptional organizational and project management skills, including the ability to plan, schedule, and successfully carry out multiple projects at the same time. In addition to experimental studies, the applicant is expected to participate in manuscript preparation and grant writing, and will be strongly encouraged to obtain independent funding.
Title: Postdoctoral Position
Institution: Jackson Laboratory for Genomic Medicine
Location: Farmington, CT
PI: Julia Oh, Ph.D. Associate Professor
Send: Cover letter and CV with three references
The Oh lab is seeking motivated computational and/or experimental scientists interested in studying the human microbiome and its impact on health. We seek to use diverse approaches in genomics, bioinformatics, synthetic biology, molecular biology, and microbiology. Our goals are to understand the complexity of our body’s microbial communities and use this information to manipulate the microbiome for therapeutic ends.
Title: Postdoctoral Position
Institution: Jackson Laboratory for Genomic Medicine
Location: Farmington, CT
Send: Cover letter and CV with contact information for three references
The Ucar lab is seeking motivated computational scientists interested in studying how epigenomes of human immune cells change with age and diseases including COVID-19. We use diverse approaches in genomics, bioinformatics, systems biology and immunology to understand how epigenetic regulation of gene expression programs are disrupted by genetics and environment. We are seeking highly-motivated individuals who have prior experience with programming and genomic data analyses. More information can be found at: https://www.ucarlab.com/
How to apply:
• Apply online: https://www.jax.org/careers-and-training/career-opportunities
• Or send your CV and contact information of three references to Dr. Ucar
• Contact information can be found at (https://www.ucarlab.com/)
Director, Clinical Genomics Laboratory
The Director, Clinical Genomics Laboratory at The Jackson Laboratory for Genomic Medicine is responsible for the overall operation, leadership, and administration of JAX’s Clinical and Preclinical Genomic Services Laboratory. The incumbent will maintain regulatory compliance in accordance with Federal, State Regulations governing clinical laboratories, and the requirements for accreditation by the College of American Pathologists, fostering a culture of innovation and transparency, while providing accurate and reliable patient test results. The Director will serve as the technical face of the JAX genomic services laboratory, providing strategic consultation and guidance to customers, external collaborators and internal stakeholders on leading edge molecular technologies, and their applications in clinical testing while maintaining a constructive and collaborative working relationship. This position reports to the Program Director, Clinical Genomics.
The Tarchini Lab at The Jackson Laboratory (http://tarchini-lab.org) is seeking a Postdoctoral Associate to complete a team currently composed of two postdocs, one research assistant and rotating students or shorter term trainees. The laboratory focuses on cell polarity mechanisms and their impact on the morphogenesis of sensory “hair” cells in the mouse auditory and vestibular organs, including hearing and balance ability. We are particularly interested in discovering new protein complexes organizing and elongating the stereocilia bundle, the apical hair cell compartment capturing sound or head movements. We are also interested in understanding how these proteins respond to damage, and more generally, to ask whether the molecular machinery assembling the stereocilia bundle during development could be leveraged to regenerate these structures after injury. We are independently funded with two R01 grants from NIH.
The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research (e.g., The Nathan Shock Aging Center and Center for Novel Alzheimer’s Disease Models), unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Translational research collaborations in genomics-based, personalized medicine are fostered through our JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.
Bar Harbor, ME
A postdoctoral training opportunity is available in the lab of Dr. Gareth Howell at The Jackson Laboratory (JAX) in Bar Harbor, Maine, to study the role of neuroinflammation and vascular health in glaucoma. Dr. Howell’s lab uses genetic and genomic approaches using mouse models to better understand the early stages of neurodegenerative diseases including glaucoma and dementias. A particular focus of this postdoctoral position will be on understanding the mechanisms by which glaucoma risk factors such as aging and intraocular pressure elevation affect the interactions between glial cells (such as astrocytes and microglia) with endothelial cells in the optic nerve head and retina. Dr. Howell, who was recently awarded a BrightFocus National Glaucoma Research Award to understand the role of the CDN2B-AS locus in glaucoma, is a co-PI on an NIH R01 grant with Dr. Richard Libby from the University of Rochester to study the endothelin system in glaucoma, and is the Diana Davis Spencer Foundation Chair for Glaucoma Research. For more information about the work of the Howell lab, visit https://www.jax.org/research-and-faculty/research-labs/the-howell-lab.
The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research, unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Translational research collaborations in genomics-based, personalized medicine are fostered through our JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.
JAX provides excellent educational and training opportunities for postdoctoral associates. Exceptional candidates are encouraged to apply for the prestigious JAX Scholar award, which supports promising early-career postdoctoral associates conducting cutting edge biomedical and basic biological research at JAX. The award includes an independent research and travel budget and a salary above our standard postdoctoral scale (https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/jax-scholars.
Bar Harbor, ME
A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia. The Trowbridge Lab offers a challenging but supportive environment. Past trainees have a noteworthy track record for obtaining grant funding and fellowships. For more information, please visit: https://trowbridgelab.com.
Postdoctoral Associate – Computational Cancer Biology
Dr. Sheng Li’s lab at JAX-GM in Hartford, CT area is seeking a computational biology postdoctoral associate who is interested in studying cancer functional genomics. The Li Lab’s primary interests are computational biology and machine learning with a focus on functional genomics in normal and cancer systems. For additional information, visit the Li Lab online.
Salary is competitive and will be supplemented with funding for computational equipment and for attending national and international conferences.