As a full-time Systems Analyst at The Jackson Laboratory, you will be part of an organization whose IT technologies are as exciting and progressive as our science. We are currently looking for motivated individuals who will work with our computational scientists, research software engineers, system administrators, and other Research IT staff to plan, design and launch efficient systems in support of scientific research functions and processes. This includes gathering data and documenting processes and requirements to help maximize Research IT systems investments.
The Carter Lab is seeking a Bioinformatics Analyst to join our research in the genetics and genomics of Alzheimer’s disease. This position will focus on using bioinformatics and computational biology analyses to formulate network-level therapeutic hypotheses to drive the development of new treatments. This analysis is a critical component of our goal to integrate diverse data resources, screen candidate compounds, and translate findings into preclinical tests using precision mouse models of disease. This work will be performed as part of two NIA-funded projects, the Emory/Sage/SGC TREAT-AD center (treatad.org) and IU/Jax/Pitt MODEL-AD center (model-ad.org), that bring together reserachers from more than a dozen institutions to develop new approaches to understanding and treating late-onset Alzheimer’s disease.These centers are components of a major open science initiative to understand and treat Alzheimer’s disease that includes the AMP-AD, ADNI, and ADSP research consortia.
We are especially interested in candidates with systems biology expertise in model organisms who are seeking to apply their innovative ideas in a translational setting. The structure of TREAT-AD and MODEL-AD enable collaborative follow-up experimentation and refinement of computational hypotheses. We are dedicated to open science and establishing an inclusive culture to expand our vision of scientific progress.
The Jackson Laboratory has an opportunity for an experienced biomedical Preclinical Lead Generation Specialist who is passionate about cultivating and maintaining strong customer interactions. The incumbent manages strategic relationships with biotechnology, academic and pharmaceutical customers to ensure revenue and management objectives are met and exceeded. Engagement with customers may be initiated via several pathways, depending on the needs of the Opportunity Development and Marketing departments:
1. By Geographic Territory - Develops and maintains strong customer relationships, providing consultative solutions and required support. Demonstrates an expertise in the utilization of the mouse as a platform of basic biomedical and drug discovery research and in the solutions provided by the Laboratory to solve research problems. Provides territory management that includes understanding the opportunity, strategic and tactical planning, execution, and reporting of results.
2. By Stage of Customer Engagement Process– Drives customer engagement between the Marketing and Sales stages for selected campaigns derived from traditional Marketing efforts and/or customer analytics efforts, taking Marketing Qualified Leads (MQLs) to Sales Qualified Leads (SQLs) and potentially further on to the generation of an opportunity, then engaging the field ODM to assist with closing the opportunity. Engages with the Marketing department and/or analytics team on health of the process,
quality of MQLs, and opportunities for improvement.
3. By Market Segment–Partners with the field ODM on selected accounts to drive Opportunity generation where sales may have decreased or where there is believed to be significant unrealized opportunity.
Measures of success include revenue performance versus established sales targets and accepted projects (won opportunities – new and renewed).
This position will be remote.
The Jackson Laboratory is hiring for a Director of Talent Acquisition within our HR Team. This position directs the talent acquisition function for The Jackson Laboratory (JAX) across all campuses in the various states and countries in which JAX operates. The Director of TA will apply innovative thought leadership and creativity to develop a world-class recruitment program that differentiates our hiring practices and candidate experience and enables JAX to scale effectively. Manages and inspires a talented team of recruiters to enable them to meet and exceed JAX’s hiring objectives. The Director of TA will lead operations to develop initiatives that tailor to each area of the organization. Will serve as the champion of candidate experience and focus on building an employer brand that will enable us to attract and retain talented and diverse candidates.
This role may be located at any one of The Jackson Laboratory’s three campuses in Sacramento, CA, Farmington, CT , or Bar Harbor ME and consideration for remote.
Project Scientists (PS) work independently in the execution of core responsibilities, but may require assistance from Senior Project Scientists to help resolve the most challenging problems. The PS position requires deep technical or operational knowledge of and expertise in products and services offered as well as inter-departmental functions and processes allowing the PS to effectively communicate project status updates, answer questions, troubleshoot challenges and understand scientific goals and deliverables for complex projects. The PS oversees the project and recognizes when the project may be going off track in the operation from the promised deliverable. Also responsible for establishing/monitoring performance measures and implementing actions. Works as part of a cross-functional team to include Project Managers, Operations, Opportunity Development Managers, and Technical Information Scientists to close deals and maximize the customer experience.
Associate/Full Computational Scientist
Structural Variation (SV)
The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a Computational Scientist to join the Lee laboratory; this is an opportunity to be involved in the use of state-of-the-art technologies to study the structural genomic variation in human biology, evolution and disease.
The Computational Scientist will work closely with a team of scientists involved in the ongoing studies which includes; accurate identification and characterization of structural variation (SV) in human and other vertebrate genomes, the development of new algorithm/approach for SV detection, and understanding genome evolution in vertebrate species and its impact on genome stability.
In addition, the Computational Scientist will be involved in exciting research programs analyzing large numbers of human genomes, activities, consortium activities, and collaborations as assigned by the PI of the lab to the extent assigned. They work closely, and are not limited to, helping interns, post-doctoral fellows, scientists and grant writing. Furthermore, they will present results to others, and have many interactions at national and international conferences and workshops.
Excellent opportunity for an experienced and successful biotech sales professional in the New England area to join The Jackson Laboratory! The incumbent identifies, negotiates and manages strategic relationships with biomedical, academic and pharmaceutical partners. Overall responsibility for ensuring revenue and management objectives are met and exceeded for assigned territory (which may include designated National Accounts). Develops and maintains strong customer relationships, providing consultative solutions and required support. Demonstrates an expertise in the utilization of the mouse as a platform of basic biomedical and drug discovery research and in the solutions provided by the Laboratory to solve research problems. Provides territory management that includes planning, implementation of plans, and reporting of results. Measures of success include revenue performance versus established sales targets and accepted projects (won opportunities – new and renewed). Relies on experience and judgment to plan and accomplish goals. Performs a variety of complicated tasks. Maintain current business while identifying and developing new business opportunities in the academic, biotechnology and pharmaceutical sectors to achieve mouse and service revenues to support the non-profit mission of The Jackson Laboratory by enabling research and contributing to surplus. A wide degree of creativity and latitude is expected. Most ODM positions are geographically organized and field based positions, however, some ODM positions may be “Inside” positions focused on developing broad based strategies for increasing transactional sales.
* Candidates must currently reside in New England to meet client needs
As a Big Data Sofware Engineer come join a dynamic team and have a high impact on big data projects at the leading edge of biomedical research.
The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a Senior Software Engineer for Data Engineering. This position reports to the Associate Director of Computational Sciences Scientific Computing (CSSC) team that is primarily responsible for developing software applications for scientific research programs.
This role will have a high impact on big data projects supporting research at the forefront of genetics and genomics. This is an exciting opportunity to work creatively solving tough problems with truly big data. The solutions you develop will lead to better understanding of highly complex biological systems, and support the search for cures to cancer, diabetes, Alzheimer's disease and other genetic disorders.
Excellent opportunity to join the Genome Technologies team at JAX at our campus in Farmington, Connecticut! Working under minimal supervision from the manager of Genome Technologies, the incumbent is responsible for testing, developing, streamlining, improving and implementing protocols (new or existing) using cutting-edge nucleic acid and library preparation, next generation sequencing (NGS) and associated technologies. The incumbent will work directly with the research and clinical labs to provide services and training. Responsibilities include testing new protocols, preparing biological samples,constructing genomic libraries and operating NGS technologies. Good knowledge in molecular biology and strong hands-on skills are critical in protocol development and implementation. Experience in automation and protocol/process scale-up highly desired, as is direct experience with operating Illumina sequencers (HiSeq, NextSeq, MiSeq) and/or PacBio Sequencers. Strong interpersonal and written and oral communications skills are required. In addition, a Technologist III will be responsible for mentoring and training other members of the lab.
The mission of the Research Information Technologies Cloud Team is to enable, facilitate, and accelerate research and discovery at the Jackson Laboratory (JAX) by harnessing the power of cloud computing and related technologies. In collaboration with partners both within JAX and at other leading research institutions, we are striving for data democratization and open science by adopting best practices of data governance and provenance, software development, high performance computing, and cloud computing. The Cloud Team thus applies best-in-class approaches for supporting a flexible and scalable infrastructure for genomic, imaging, and other types of biological data.
Senior Computational Scientists will closely work with the research faculty and scientists across all campuses of JAX on projects of wide ranging complexity from a diverse array of biomedical disciplines such as cancer biology, aging, immunology, infectious diseases, metabolomics, neural disorders, muscular disorders, Biostatistics & Statistical Genetics, and stem cell & developmental biology. Research projects will involve the large-scale collection, processing, and integration of biological data, with emphases toward imaging, genomics, and metabolomics.
A project manager is responsible for understanding and implementing complex research goals in the confines of time and budget. This is accomplished by coordinating a vast array of research services available and using best practice of project management. The ideal candidate will have a firm foundation of scientific understanding, associated with the use of mouse models of human disease, model generation and/or in vivo pharmacology. This fast pace position requires excellent organizational and communication skills, along with the ability to think critically and recommend best solutions to meet project goals.
The Stitzel Lab seeks a highly motivated, innovative, driven, and independent bioinformatics analyst who will perform processing, analysis, and visualization of the vast next generation sequencing data generated by ‘omics experiments such as ATAC-seq, RNA-seq, and single cell sequencing and collaborate, integrate, and communicate with the bench scientists conducting the experiments and generating the data. The Stitzel Lab’s overarching goal is to understand the genomic and cellular underpinnings of islet (dys)function and diabetes. They employ innovative (epi)genomic profiling and single cell genomic technologies, human cellular and mouse models, and CRISPR/Cas9 (epi)genome editing platforms to identify key genes and pathways controlling human islet cell identity and function and to understand how diabetes-associated DNA sequence variants and environmental stimuli/stressors alter these programs to contribute to islet failure in diabetes.
This is a highly collaborative and integrated environment with multiple projects. Dr. Stitzel will supervise this position directly. Thus, he will determine assignment and prioritization of projects, as well as assessment of progress on projects, in direct consultation with the bioinformatics analyst.
The Strategic Insights & Innovation Senior Analyst reports to the Manager, Strategic Marketing and is responsible for identifying and evaluating new business and new product opportunities both within and outside of currently served markets and technical capabilities. The role requires the ability to work well with teams, help create program visions, and pull and analyze data with ease. The individual will assess market opportunities beyond core adjacencies, and will assist in the prioritization of efforts across disparate business areas. This position is critical to achieving overall business growth goals and will work intimately with New Product Development and Product Management to achieve those goals.
Computational Postdoctoral Associate
Computational biology is critical not only to the processing and manipulation of data, but to the scientific discovery process itself. Our lab empowers computational biologists to make discoveries by providing a rich work environment for computational/mathematical analysis of biological systems, access to novel data and computational infrastructure, resources to conduct new experimental measurements, and partnerships with experimental colleagues with shared interests.
As of December 2019, the Chuang Lab is seeking a postdoctoral scientist to join our projects combining computational and experimental approaches to study cancer. Our current projects are at the intersections of cancer biology, machine learning, genomics, image analysis, and pathology. This is a fast-moving field with tremendous opportunities to understand cancer and impact patient outcomes.
New team members will have unique opportunities to investigate mechanisms of cancer, to design new studies, and to develop novel artificial intelligence approaches to mine these data. Our lab seeks to understand how tumor ecology and evolution impact susceptibility and response to immunotherapy, targeted therapy, and chemotherapy. We interrogate these questions by generating data from clinical samples and model systems (xenografts, organoids) and by mining large cancer genomic and imaging datasets using techniques such as deep learning and evolutionary modeling. This position is supported by an R01 grant from the NCI awarded through 2023.
While our lab focuses on computational approaches, we also generate our own data by making use of the extensive scientific services at JAX and in collaboration with many experimental colleagues. These include clinical and experimental groups at JAX (Robson, Palucka, Liu, Anczukow-Camarda, et al.) and with external partners (NCI PDXNet, Yale, Northwestern, UCSD, et al). We have particular access to patient-derived xenografts (PDXs) due to Prof. Chuang's position as co-PI of the National Cancer Institute's PDXNet Consortium Data Commons and Coordination Center, in addition to the extensive data and experimental resources for PDXs at JAX. Thus candidates will have novel opportunities at the intersection of data interpretation, algorithms, and experimental design.
For this position, the ideal candidate will have Ph.D. experience in computational biology, cancer biology, evolutionary biology, digital pathology, or a similar discipline. Outstanding applicants new to computational biology will also be considered as the lab has an extensive record of training candidates who originally studied in other fields, including physics, applied math, computer science, electrical engineering, and experimental molecular biology. A particular area of growth for the lab is the combination of genomic and pathological analysis, and those with a medical background in pathology but a strong interest in computational approaches are encouraged to apply. Computing (programming, data analysis, statistical inference, etc), publication, and communication skills will be essential. Across these backgrounds, enthusiasm and aptitude for computational biology are what define the lab.
Interested and qualified individuals should send a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references to Dr. Jeff Chuang at firstname.lastname@example.org
Christine Beck Lab
About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston in the heart of Connecticut's growing bioscience industry. Our mission at JAX-GM is to discover the complex causes of disease, develop diagnostics and therapeutics, and ultimately empower the global medical community.
As a Postdoctoral Associate in the Beck laboratory, you will join a growing team of researchers focused on how the repetitive DNA content of the human genome contributes to the regulatory landscape of our genomes. We are currently seeking a postdoctoral researcher who has experience in molecular genetics work to continue an exciting project related to mobile element biology in human genomes. Experience with molecular and biochemistry is prioritized, and a willingness to learn computational techniques for genomic analyses is key for this position. The applicant needs to have a deep understanding of the biology of the human genome, and of how to frame a hypothesis. The desire to pursue interesting questions, and to find the true answers to them is paramount.
Our team consists of two graduate students, a computational scientist and a research associate. Your job would be to pursue your research, and (if possible) independent funding opportunities in this supportive and inquisitive team, and to build upon your current knowledge in a productive postdoctoral career. The position is fully funded and awaiting the proper, enthusiastic applicant.
• PhD (or nearing completion of PhD degree)
• Ability to demonstrate effective productivity, presentations, and bench science adaptability.
• Ability to interact with a diverse team of individuals in a productive, professional and positive manner to enhance the outcome of the goals of the research program
• Established understanding of good safety practices and a demonstrated history of safe conduct
• Proven ability to organize time effectively and work under time constraints, meet deadlines and prioritize work
• Background and advanced knowledge in genetics
• Desired techniques include mammalian cell/tissue culture, human cell culture (including ES cells) molecular cloning and verification, PCR, qPCR, and basic biochemical techniques
• Productivity exhibited in accepted and in press publications
• Experience in library preparation for next generation sequencing
• Experience with ATAC-seq, Hi-C, and ChIP-seq
• Understanding and experience with computational analysis of sequencing data
• Stem cell culturing experience
• Mentoring experience
The Lee lab is seeking a highly-motivated postdoc with strong background in bioinformatics and computational biology. The Lee Lab at the Jackson Laboratory for Genomic Medicine uses state-of-the-art technologies to study structural genomic variation in human biology, evolution and disease. Ongoing studies in the lab include:
1. accurate identification and annotation of structural variation in human and other vertebrate genomes;
2. identification and characterization of genetic aberrations associated with congenital birth defects;
3. the development of new diagnostic assays and platforms for genomic medicine;
4. understanding genome evolution in vertebrate species and its impact on genome stability
Bioinformatics - Postdoctoral Associate
Dr. Peter Robinson Lab
The Jackson Laboratory
Full time position for a Bioinformatics Postdoctoral Associate to join an interdisciplinary team of computational biologists, clinicians, and ontologists who are working together to develop machine-learning and semantic algorithms for the analysis of clinical data. The position is located at the Jackson Laboratory for Genomic Medicine in Farmington, CT
We are looking for an enthusiastic individual who will take a hands-on, problem-solving approach to clinical machine-learning, collegial work environment that is infused with intellectual rigor. The right candidate will have an outstanding academic record and strong communication skills, will demonstrate innovative and analytical thinking, and will enjoy working as part of the CTSA National Center for Data to Health (CD2H; https://ctsa.ncats.nih.gov/cd2h/). The new National Center for Data to Health (CD2H), a multi-institutional consortium led by OHSU, has been awarded a $25 million grant from the National Institutes of Health to support the use of health data, algorithms and information systems to bridge basic science and clinical research and to foster collaboration across more than 50 medical research institutions within the national Clinical and Translational Science Awards network.
SUPERVISOR OF CLINICAL VIROLOGY
Under the general supervision of the Clinical Laboratory Manager and/or Clinical Laboratory Director, provides assistance in planning, organizing and preparing laboratory exercises in support of the Clinical Genomics Laboratory (CGL) at JAX Genomic Medicine. A primary responsibility is to supervise laboratory personnel, overseeing clinical/production testing and troubleshooting issues if they arise. This position requires a high degree of technical abilities in molecular biology and virology. The position also requires administrative duties such as weekly laboratory updates, management of laboratory inventory, and other duties deemed necessary by the Clinical Laboratory Manager and/or Clinical Laboratory Director.
Certification: ASCP Certification in Molecular Biology
As a full time System Engineer at The Jackson Laboratory, you'll be part of an organization whose IT technology is as exciting and progressive as our science. We are currently looking for motivated individuals who will work with our computational scientists, system administrators, and other Research IT staff to design, configure, and implement efficient research computing systems in support of scientific research functions and processes
Postdoctoral Research Associate (wet lab)
Ruan Lab at the Jackson Laboratory for Genomic Medicine
The Ruan Lab is currently funded by two NIH center grants (4DN and ENCODE), and supported by the Roux family endowment and the JAX 3D Genome Center. Its primary mission is to develop cutting-age technologies for comprehensive mapping of 3D genome organizations in human and mouse, and to uncover the molecular mechanisms that control important genome functional modulation including gene transcription regulation. In this position within the Ruan Lab and the JAX 3D Genome Center, the incumbent will provide scientific and programmatic leadership in the strategic discussion, technological development, experimental implementation, and data analysis/ interpretation, etc. The role will involve significant interaction and collaboration within the center, the Jackson Laboratory, and with external partners, particularly within the 4DN and ENCODE consortia. This position offers great growth opportunity to contribute both in novel technology development and advanced genomic discoveries that have immediate relevance in genetics and clinical significance in an innovative and fast-paced team environment. For more information on the Ruan Lab’s research and goals, visit: https://www.jax.org/research-and-faculty/research-labs/the-ruan-lab.
- PhD in genomics, genetics, molecular biology, and related areas
- Strong background in genomics and epigenomics, chromatin biology
- Solid publication track record
- Experiences with microfluidics and single cell analysis are desirable
Please send a curriculum vitae (CV) to Dr. Yijun Ruan (email@example.com).