The Jackson Laboratory

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Job Locations US-CT-Farmington
Posted Date 5 days ago(3/31/2020 12:15 PM)
Lee Lab Cell Biology Internship   Summary   We are seeking a highly motivated individual to join the Lee Lab research team as a 2020 summer intern. This position is accountable for performing the basic laboratory and/or related support tasks for canine induced pluripotency stem cell (iPSC) project at Dr. Charles Lee’s Lab at the Jackson Laboratory for Genomic Medicine located at Farmington, CT. Dogs and humans have many inherited genetic diseases in common and conditions that are increasingly prevalent in humans also occur naturally in dogs. The use of dogs for the experimental and clinical testing of stem cell and regenerative medicine products would benefit canine health and welfare and provide relevant animal models for the translation of therapies to the human field. The project focus is to establish canine iPSC cell lines for disease modeling.     About Your JAX Internship Experience   Join peers selected from educational institutions across the country for a summer of professional growth and career exploration. As a JAX Intern you will receive a dedicated mentor in your department and connect with your fellow interns through JAX-sponsored activities.   Responsibilities   The intern will be involved in the procedure of deviating and characterizing canine iPSC cell lines. The candidate will be trained to design, optimize, and execute experiments under the supervision of experienced colleagues.   - Daily maintenance of tissue culture - Perform characterization experiements such as DNA, RNA isolation, RT-PCR, immunocytochemistry staining et al. with well recorded experiment notes - Isolation of peripheral blood mononuclear cell, skin fibroblast cells, bone marrow cells et al. - Perform basic lab maintenance - Reagent/solution preparation   Expected Outcomes   - Development of basic and advanced skills of tissue culture and molecular characterization experiments, especially in iPSC deriviation and maintenance procedure - Other routine wet lab techniques in a cell biology lab - Knowleadge of the features, derivatiion, maintenance, differentiation and characterization of pluripotency stem cells - Knowleadge and skills of of iPSC based disease modeding         Desired Qualifications   JAX encourages application from a diverse mix of educational experiences and backgrounds. Preferred qualifications include:   - Basic knowledge of research protocols, principles and procedures - Basic skills of scientific techniques such as tissue culturing, reagent/solution preparation, staining, PCR etc. - Basic knowledge of experimental design, mathematics, statistics, computer applications, laboratory equipment and procedures - Basic knowledge of a science such as; chemistry, biology, microbiology, pharmacology - Basic knowledge of physical and data resources in application scientific disciplines - Oral and written communication skills - Ability to identify, produce, organize, analyze, evaluate and interpret data   About JAX   The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,300 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries. JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine! Employment will require successful completion of references, background check, and pre-employment physical. Employment Non-Discrimination   The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws. Learn more about career opportunities at JAX: http://www.jax.org/careers.
Job ID
2020-27730
Job Locations US-CT-Farmington | US-ME-Bar Harbor
Posted Date 2 weeks ago(3/25/2020 7:47 PM)
This position is responsible for a wide range of administrative tasks and special projects in support of members of the Clinical Genomics Team, including the Clinical KnowledgeBase (CKB), reporting to the Senior Director, Product Innovation & Commercialization. The successful candidate will join a team dedicated to providing the highest quality services and data for research and clinical applications.   The dynamic nature of this work environment requires that the ideal candidate have exemplary time management skills, be comfortable under deadlines, proficient in all Microsoft Office products, able to work in a database, strong writing skills for all correspondence and the ability to identify and anticipate highly varied needs.  To perform this job successfully an individual must be able to confidentially handle highly sensitive information while exercising professional discretion. To learn more about this group at JAX, visit: https://www.jax.org/clinical-genomics.
Job ID
2020-27522
Job Locations US-ME-Bar Harbor | US-CT-Farmington
Posted Date 3 weeks ago(3/13/2020 6:16 PM)
Reporting to the JAX® Mice, Clinical & Research Services (JMCRS) Creative & UX Strategy Lead and taking significant direction from the Senior Marketing Manager and Content Manager, the Digital Designer translates business goals and initiatives into compelling, innovative, and clear digital and motion communications. The Digital Designer will need to be driven to identify and deliver good creative digital design assets, working with the design team to expand and build upon creative concepts and ideas. The Digital Designer will have excellent and current creative and design trend knowledge and skills (from branding identity and package design, digital, to time-based media).   The Digital Designer is able to problem solve and must be a team player with strong interpersonal and communication skills who is highly organized with ability to be flexible and adapt to changing priorities.  This individual should be comfortable owning projects from start to finish as well as providing direction and guidance to other designers.   The Digital Designer will collaborate across JAX, working closely with Strategic Communications and JAX Creative to bring our brand to life using graphic design, typography and digital/interactive design. The ideal candidate thrives in high-pressure, fast-paced environments and can manage competing priorities to execute and deliver high-quality work to our customers. This individual is self-motivated, takes challenges head on and explores multiple solutions to every problem   This position will be an integral part of the JMCRS Marketing team, tasked with providing top-notch marketing solutions that enhance and support the Laboratory’s strategic priorities. Requires independent, creative thinking within the context of established brand standards, willingness to take and measure calculated risks, and operate in a customer-focused environment. Position will have interaction with staff at all levels of the institution, as well as external partners and constituents.
Job ID
2020-27698
Job Locations US-CT-Farmington
Posted Date 3 weeks ago(3/12/2020 12:24 PM)
Bioengineering Intern   We are looking for a student intern to design, test and optimize custom devices for life science research. The intern will be supervised by an experienced biomedical engineer in the Schomer Lab (sponsored by the Lau Lab) at Farmington, CT. The position requires basic understanding in electronics and some experience in assembling small devices; for example, if you can follow a manual and assemble a remote-controlled toy car or drone, you will be able to complete the tasks. Some custom design and optimization will be carried out by the intern; therefore, independent thinking, attention to details and a high standardard for quality are required. The intern will have the opportunity to interact with researchers in genomic medicine and cancer biology in an enriched learning environment. This position is well suited for a biomedical engineering student with interests in next-generateion life science research.   Expected Outcomes The intern will learn how to set up and optimize small laboratory devices for specific biomedical applications. The intern will also develop skills in biomaterial and cell-material interface design and engineering. Successful completion of the tasks that lead to novel findings of cell behavior will entitle co-authorship for scientific publications.
Job ID
2020-27678
Job Locations US-CT-Farmington
Posted Date 4 weeks ago(3/11/2020 3:05 PM)
Associate/Full Computational Scientist Structural Variation (SV)     The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a Computational Scientist to join the Lee laboratory; this is an opportunity to be involved in the use of state-of-the-art technologies to study the structural genomic variation in human biology, evolution and disease.   The Computational Scientist will work closely with a team of scientists involved in the ongoing studies which includes; accurate identification and characterization of structural variation (SV) in human and other vertebrate genomes, the development of new algorithm/approach for SV detection, and understanding genome evolution in vertebrate species and its impact on genome stability.   In addition, the Computational Scientist will be involved in exciting research programs analyzing large numbers of human genomes, activities, consortium activities, and collaborations as assigned by the PI of the lab to the extent assigned. They work closely, and are not limited to, helping interns, post-doctoral fellows, scientists and grant writing. Furthermore, they will present results to others, and have many interactions at national and international conferences and workshops.
Job ID
2020-27686
Job Locations US-CT-Farmington
Posted Date 4 weeks ago(3/11/2020 10:25 AM)
Postdoctoral position available in Functional (epi) genomics of pancreatic islet dysfunction in type 2 diabetes PI: Michael L. Stitzel, Ph.D. The Jackson Laboratory for Genomic Medicine Farmington, CT The Stitzel lab at The Jackson Laboratory’s Genomic Medicine campus in the Hartford, CT area is seeking an independent, driven PhD-level scientist (<2 years previous postdoc experience) in integrated functional (epi)genomics and/or quantitative genetics to join our growing, externally-funded research program. Our overarching goal is to understand the genetic and cellular underpinnings of islet (dys)function and diabetes. We employ innovative (epi)genomic profiling and single cell genomic technologies, mouse models, and CRISPR/Cas9 (epi)genome editing platforms to identify key genes and pathways controlling human islet cell identity and function and to understand how diabetes-associated DNA sequence variants and environmental stimuli/stressors alter these programs to contribute to islet failure in diabetes.     Interested and qualified individuals should submit a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references at time of application. Our research group is diverse and collaborative, and we seek to produce top notch science and foster the development of outstanding, independent scientists through critical but nurturing mentorship and interdisciplinary, collaborative efforts.
Job ID
2019-27183
Job Locations US-CT-Farmington
Posted Date 4 weeks ago(3/11/2020 10:24 AM)
Postdoctoral Associate Palucka Lab     The Palucka Lab at JAX-GM is currently seeking motivated scientists interested in analyzing and integrating RNA-seq, ATAC-seq, and genetic data. Additional tasks will include pre-processing of raw sequencing files, as well as more advanced integrative models using machine learning algorithms.    In addition, JAX Postdoctoral Associates benefit from: • Research training and mentorship from award-winning faculty • Individualized career advising and a dedicated Postdoc Program Office • Superior scientific services and unparalleled mouse resources • A uniquely collaborative academic research environment • Guidance from JAX's Postdoctoral Training Committee to help you succeed • Professional skills workshops including JAX's holistic The Whole Scientist course • Free access to JAX’s world-renowned Courses & Conferences programs • Outstanding benefits and salary compensation above the NIH scale • Generous relocation assistance and free on-campus parking
Job ID
2019-26908
Job Locations US-CT-Farmington
Posted Date 1 month ago(3/3/2020 10:25 AM)
Computational Scientist  (Assistant/Associate/Full)     The Jackson Laboratory is immediately seeking a Computational Scientist at the level (Assistant/Associate/Full Computational Scientist) to join our Computational Sciences group. This position offers the opportunity to make leading contributions to cutting edge research in mouse genetics, disease biology, and translational research in collaboration with the faculty and genetic resource scientists and clients of The Jackson Laboratory (JAX). Cross campus and industry collaborations are encouraged.   This position is available in Farmington, CT. The Computational Scientist hire is expected to make periodic multi-day work visits to the Bar Harbor campus of The Jackson Laboratory.
Job ID
2020-27677
Job Locations US-CT-Farmington
Posted Date 1 month ago(2/26/2020 1:38 PM)
Postdoctoral position available in metabolomics PI: Shuzhao Li, Ph.D. The Jackson Laboratory for Genomic Medicine Farmington, CT SUMMARY We are looking for a talented Postdoctoral associate to apply mass spectrometry based metabolomics to genomic medicine, and to develop novel methods and applications.   The ideal candidate will have a deep understanding of mass spectrometry and metabolomics, and a passion to impact biomedical research and practice. The incumbent will work closely with a team of chemists, biologists and computational scientists. The Jackson Laboratory provides unparalleled support of professional development. Metabolomics has evolved to a stage to employ rich data to guide experimental design and method development. The Li lab has recognized strengths in computational methods, integration with big data, and cutting-edge applications to human immunology and ImmunoMetabolomics. This position has the unique opportunity to interface with large scale projects on genomics, transcriptomics, microbiome, single cell technologies and cellular engineering, and to take leadership in innovations.   Qualifications: • Recent PhD related to metabolomics, mass spectrometry, analytical chemistry • Experience in LC-MS, MS/MS, compound identification, isotope tracing • Experience in Orbitrap instruments is advantageous • Experience in metabolomics data processing and analysis • Track record of productivity supported by first-author publications in peer-reviewed journals • Outstanding writing and communication skills, with an ability to work both independently and within collaborative teams productively   Candidates will be encouraged to apply for competitive foundation and federal training fellowships and awards. Exceptional candidates also have the opportunity to become a JAX Postdoctoral Scholar, a selective award that includes an independent research budget, travel funds, and a salary above the standard postdoctoral scale.   Interested and qualified individuals should send a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references to Dr. Shuzhao Li at shuzhao.li@jax.org.   Our research group is diverse and collaborative, and we seek to produce top notch science and foster the development of outstanding, independent scientists through critical but nurturing mentorship and interdisciplinary, collaborative efforts.
Job ID
2020-27534
Job Locations US-CT-Farmington
Posted Date 2 months ago(2/19/2020 9:49 AM)
Bioinformatics - Postdoctoral Associate Dr. Peter Robinson Lab The Jackson Laboratory   Full time position for a Bioinformatics Postdoctoral Associate to join an interdisciplinary team of computational biologists, clinicians, and ontologists who are working together to develop machine-learning and semantic algorithms for the analysis of clinical data. The position is located at the Jackson Laboratory for Genomic Medicine in Farmington, CT   We are looking for an enthusiastic individual who will take a hands-on, problem-solving approach to clinical machine-learning, collegial work environment that is infused with intellectual rigor. The right candidate will have an outstanding academic record and strong communication skills, will demonstrate innovative and analytical thinking, and will enjoy working as part of the CTSA National Center for Data to Health (CD2H; https://ctsa.ncats.nih.gov/cd2h/). The new National Center for Data to Health (CD2H), a multi-institutional consortium led by OHSU, has been awarded a $25 million grant from the National Institutes of Health to support the use of health data, algorithms and information systems to bridge basic science and clinical research and to foster collaboration across more than 50 medical research institutions within the national Clinical and Translational Science Awards network.
Job ID
2020-27646
Job Locations US-CT-Farmington
Posted Date 2 months ago(2/18/2020 5:33 PM)
VARIANT ASSAY INTERPRETATION SCIENTIST Clinical Scientific Curator   The Clinical Scientific Curator for the Clinical Genomics and Genetics Services unit at The Jackson Laboratory for Genomic Medicine will critically evaluate and interpret cancer genomic variants from curation into the JAX Clinical Knowledgebase (CKB). The Clinical Scientific Curator will assimilate and integrate data from scientific literature related to pathogenicity and predictive efficacy in a format compatible with clinical reporting. The Content Curator will also perform wet lab work related to Clinical Genomics activities, and will assist in quality assurance and quality control of all data within CKB.
Job ID
2020-27605
Job Locations US-CT-Farmington
Posted Date 2 months ago(2/17/2020 2:14 PM)
Clinical Genomic Analyst II   The Clinical Genomic Analyst will contribute to clinical operations and clinical product development at The Jackson Laboratory for Genomic Medicine by working closely with CG Scientists, management and the Clinical Laboratory Director (CLD). This role will support production by performing essential data analysis, processing and reporting functions in a CLIA/CAP accredited laboratory. The Clinical Genomic Analyst role involves analysis, classification and interpretation of cancer genomic variants using scientific literature as well as genomic databases. The ideal candidate for the Clinical Genomic Analyst role at JAX will demonstrate working knowledge across many fields including bioinformatics, computational sciences, clinical laboratory sciences and genetic pathology. This position is for an individual who understands the different components of a genetic test and has the experience/exposure in clinical genetic testing environment.
Job ID
2020-27632
Job Locations US-CT-Farmington
Posted Date 2 months ago(2/13/2020 2:11 PM)
 Scientific Software Engineer (Associate/Full/Senior) Data Science Focus   Come join the development team of the JAX Clinical Knowledgebase (CKB). CKB is a dynamic digital resource for interpreting complex cancer genomic profiles and is used by clinicians and researchers from around the world to connect cancer variants to therapies and clinical trials.  Come be a part of the fight against Cancer!   This position is available immediately for a Scientific Software Engineer (Associate/Full/Senior) with a large focus on data science, as a part of the Computational Sciences Scientific Computing group at The Jackson Laboratory for Genomic Medicine in Farmington, CT.  Play a pivotal role in investigating potential integration opportunities as well as helping to lead the effort to translate those opportunities into mature software solutions.  Use your skills to propose, analyze, prototype new solutions as well as run novel analysis over the existing systems.  Leverage NLP, ML and AI to develop novel approaches to help streamline curation as well as add additional value to existing data. This is an exciting opportunity to work on challenging problems at the interface of biology, computer science and data science.  CKB is a leading cancer knowledgebase, with partners around the world integrating CKB data, join the team and help push CKB to the next level.
Job ID
2020-27622
Job Locations US-CT-Farmington
Posted Date 2 months ago(2/5/2020 4:55 PM)
Do you want to support the next generation of scientists? Are you excited about diversifying the face of biomedical research? We invite you to join the highly collaborative Genomic Education team in a dynamic role as Program Administrator for our on-campus education and training programs.   Help our fantastic community of students and early-career researchers thrive during their experience at JAX. Help us broaden our reach regionally, nationally, and internationally to recruit new audiences to our transformative programs.
Job ID
2019-27111
Job Locations US-CT-Farmington
Posted Date 2 months ago(2/4/2020 5:46 PM)
Postdoctoral position available in Multi-omics data analysis in immunology PI: Shuzhao Li, Ph.D. The Jackson Laboratory for Genomic Medicine Farmington, CT   The Li lab at The Jackson Laboratory’s Genomic Medicine campus in Farmington CT, is seeking an independent, driven PhD-level scientist (<2 years previous postdoc experience) in computational systems biology, especially in the area of integrating transcriptomics, metabolomics, proteomics, lipidomics and microbiome in immunological projects. Our goal is to model human immune system through multi-omics and multiscale data. This involves data collected from vaccine and infection studies, and from NIH data repositories. We employ statistical, data mining and machine learning approaches. The new immunometabolomics program we are building at JAX will add high-resolution chemistry into the field of systems immunology.   Qualifications: • PhD in bioinformatics, computational biology, systems biology, or other quantitative science • experience in programming language (such as Python or R) and omics data analysis. • Experience in cloud computing • Track record of productivity supported by first-author publications in peer-reviewed journals • Outstanding writing and communication skills, with an ability to work both independently and within collaborative teams productively   Candidates will be expected to apply for competitive foundation and federal training fellowships and awards. Exceptional candidates also have the opportunity to become a JAX Postdoctoral Scholar, a selective award that includes an independent research budget, travel funds, and a salary above the standard postdoctoral scale.   Interested and qualified individuals should send a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references to Dr. Shuzhao Li at shuzhao.li@gmail.com. Our research group is diverse and collaborative, and we seek to produce top notch science and foster the development of outstanding, independent scientists through critical but nurturing mentorship and interdisciplinary, collaborative efforts.
Job ID
2020-27533
Job Locations US-CT-Farmington
Posted Date 2 months ago(1/29/2020 12:49 PM)
With oversight from the Scientist of Clinical Assay Development, the Technologist II, Clinical Assay Development (CLIA) will be responsible for processing research samples using cutting-edge technologies for nucleic acid analysis, including but not limited to next-generation sequencing, Sanger sequencing, ddPCR, methylation array and associated sample preparation technologies. These activities will be performed under CLIA/CAP regulations and will directly impact human health and thus must meet the highest possible standards for quality and integrity. The Technologist I, II or III, Clinical Assay Development (CLIA) are distinguishable primarily by level of experience, supervision required, proficiency in problem solving, certification and wider range of training
Job ID
2020-27580
Job Locations US-CT-Farmington | US-ME-Bar Harbor
Posted Date 2 months ago(1/28/2020 5:26 PM)
Systems Analyst - Cloud   The Jackson Laboratory is an independent, nonprofit biomedical research institution internationally recognized for its research excellence and world-class faculty, who perform leading-edge research in the fields of human genomics and mouse genetics. At JAX, our Information Technology is as exciting and progressive as our cutting-edge science.    The Systems Analyst will plan, design, and launch efficient systems in support of scientific research in the Cloud to assist the Research IT team. The ideal candidate will have a complex and theoretical understanding and hands-on experience in Cloud environments, High Performance Computing (HPC) and scientific data management, as well as working collaboratively with researchers and Information Technology staff.
Job ID
2020-27492
Job Locations US-CT-Farmington
Posted Date 2 months ago(1/27/2020 10:57 AM)
Research Assistant III - Cell Biology Palucka Lab Farmington, CT    The incumbent will support a focused project on the immune response in the lung with work including cell culture to establish lung organoids and air-liquid cultures. Familiarity with flow cytometry and immunological assays is a plus, as these lung organoids will be used for co-cultures with dendritic cells and T cells to study the induction and regulation of immune response to respiratory viruses.  
Job ID
2020-27532
Job Locations US-CT-Farmington
Posted Date 2 months ago(1/26/2020 8:25 PM)
Postdoctoral Associate Hinson Lab     The Hinson lab is seeking an independent, highly-motivated PhD-level scientist (<2 years postdoc experience) with a strong background in cell biology to join our somatic cell genome-editing (SCGE) program funded by NIH U01 EB028898. This four-year academic project aims to: 1) interrogate human cardiac microtissues by comprehensive assessment of cardiac physiology in combination with single-cell transcriptomics to identify efficacy and adverse consequences of somatic cell genome editing targeted to heart failure-associated genetic loci, and 2) engineer autologous cardiac microtissues assembled with two distinct classes of macrophages to study cardiac function and genome editing reagents.   The Hinson lab at the Jackson Laboratory for Genomic Medicine and UConn Health studies human cardiovascular disorders especially heart failure using a combination of approaches including genome editing, pluripotent stem cell technology, genomics assays, and tissue engineering. We are a highly-collaborative multi-disciplinary team that includes expertise in genome biology, computation biology, tissue engineering and clinical cardiovascular medicine.   QUALIFICATIONS - Ph.D. in cell biology, molecular biology, genetics, or related field of study. - Prior research experience in at least two of the following areas: pluripotent stem cell biology and differentiation, cellular physiology, next-generation genome sequencing assays especially RNA-seq, and tissue engineering especially involving engineered cardiac tissues. - Experience in single cell technologies for transcriptomics, flow cytometry (or other forms of cytometric analyses), cellular histology and confocal microscopy especially live-cell imaging is particularly desirable. - Candidates should have a publication record in peer-reviewed journals. - Excellent writing and communication skills, able to work independently and effectively with other members in a productive team. - Experience with R, Python or similar statistical package is helpful, as well as experience with clustering, pathway, genetic and genomic data analyses and bioinformatics. **Please submit your current CV, at least 2 letters of reference, and 1-page (maximum) statement of Research Interests and Career Goals at time of application.**   We are a diverse and inclusive research group, aspiring to produce top science and scientists through attentive and progressive mentoring and interdisciplinary teamwork.
Job ID
2019-27084
Job Locations US-CT-Farmington
Posted Date 2 months ago(1/20/2020 11:26 AM)
As a Big Data Sofware Engineer come join a dynamic team and have a high impact on big data projects at the leading edge of biomedical research. The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a Senior Software Engineer for Data Engineering. This position reports to the Associate Director of Computational Sciences Scientific Computing (CSSC) team that is primarily responsible for developing software applications for scientific research programs.  This role will have a high impact on big data projects supporting research at the forefront of genetics and genomics. This is an exciting opportunity to work creatively solving tough problems with truly big data. The solutions you develop will lead to better understanding of highly complex biological systems, and support the search for cures to cancer, diabetes, Alzheimer's disease and other genetic disorders.
Job ID
2018-25477