The Jackson Laboratory

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Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(2/11/2020 7:43 AM)
The Tewhey Lab at The Jackson Laboratory in Bar Harbor, Maine is seeking a Postdoctoral associate to join our team of scientists working to understand the precise genetic mechanisms underlying complex traits, and the impact human genetic variation has on gene regulatory function. Our group develops and applies novel high-throughput genetic techniques (e.g. MPRA and CRISPR based screens) to comprehensively characterize non-coding regions of the genome, in both mouse and human, to interpret the regulatory grammar of gene expression.    
Job ID
2018-25153
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(2/11/2020 7:42 AM)
The Lu Lab (http://www.lusystemsbio.com) at The Jackson Laboratory is currently seeking motivated and innovative scientists for academic postdoctoral positions at the cutting edge of computational systems biology. The Lu lab, in Bar Harbor, Maine, is focused on the development and application of computational modeling and bioinformatics methods to construct gene regulatory networks and predict network dynamics. The candidates will participate in a multidisciplinary environment and have opportunities to interact with experimental biologists within the Jackson Laboratory, the Jackson Laboratory for Genomic Medicine at Farmington, Connecticut, and outside the institution. Postdoctoral associates will have access to high-quality data measured by state-of-the-art experimental techniques, high-performance computing facilities and the largest repository of mouse resources in the world.  
Job ID
2018-24836
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(2/11/2020 7:40 AM)
A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia. The Trowbridge Lab offers a challenging but supportive environment. Past trainees have a noteworthy track record for obtaining grant funding and fellowships. For more information, please visit: https://trowbridgelab.com.
Job ID
2018-25929
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(2/11/2020 7:35 AM)
  The Ke Lab has a postdoctoral associate opening in computational biology at The Jackson Laboratory in Bar Harbor, Maine. The Ke Lab focuses on RNA, a central node of genetic information flow from DNA to protein (https://www.jax.org/research-and-faculty/faculty/shengdong-ke). Malfunction of RNAs leads to many human diseases, including neurological diseases and cancer. To thoroughly address fundamental molecular mechanisms of RNA genomics, the Ke lab utilizes multidisciplinary approaches, including computational biology, biochemistry, innovative biotechnologies, genetics and molecular biology. We are especially interested in the fundamental mechanism of m6A RNA genomics; and regulation of m6A RNA genomics in neurological disease and cancer, using mouse and human iPS models.  
Job ID
2018-25557
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(2/11/2020 7:29 AM)
The Ke Lab is seeking a Research Data Analyst to join The Jackson Laboratory in Bar Harbor, Maine. The lab focuses on RNA, a central node of genetic information flow from DNA to protein. Malfunction of RNAs leads to many human diseases, including neurological diseases and cancer. To thoroughly address fundamental molecular mechanisms of RNA, the Ke Lab utilizes multidisciplinary approaches, including cutting-edge computational biology, biochemistry, innovative biotechnologies, genetics, and molecular biology. Working collaboratively with bench scientists conducting experiments, the research data analyst will use existing and develop new computational tools to analyze RNA-seq, CLIP, CHIP, DNA methylation, and proteomics datasets. Applicants are expected to have proficiency in Python, Perl, or R programming languages.   The Research Data Analyst I will be directly supervised, working closely with the manager, who will assign and prioritize projects in consultation with the analyst. The Research Data Analyst II will work independently, apply advanced problem-solving skills, and may participate in training of Research Data Analyst I colleagues. To learn more about the Ke Lab, please visit https://www.jax.org/research-and-faculty/faculty/shengdong-ke.
Job ID
2019-27278
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(2/11/2020 7:23 AM)
  The Jackson Laboratory is a world leader in mammalian genetics.  JAX is passionate about its mission of discovering precise genomic solutions for disease and empowering the global biomedical community in the shared quest to improve human health.   The Ke Lab is seeking a postdoctoral associate at The Jackson Laboratory in Bar Harbor, Maine. The Ke Lab focuses on RNA, a central node of genetic information flow from DNA to protein (https://www.jax.org/research-and-faculty/faculty/shengdong-ke). Malfunction of RNAs leads to many human diseases, including neurological diseases and cancer. To thoroughly address fundamental molecular mechanism of RNA, the Ke lab utilizes multidisciplinary approaches, including cutting-edge computational biology, biochemistry, innovative bio-technologies, genetics and molecular biology. We are especially interested in m6A RNA biology: 1) the fundamental mechanism of m6A RNA biology, and 2) the biological effects of m6A regulation in nerve system, using mouse and human iPS models. (References: 1] Ke, S. et al. m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover, Genes & Development 2017, 31: 990-1006; 2] Ke, S. et al. A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation, Genes & Development 2015, 29:2037-53.)    
Job ID
2018-25230
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(2/11/2020 7:23 AM)
Chemistry and physics meet biology and genomics in the Mass Spectrometry and Protein Chemistry (MSPC) Service at The Jackson Laboratory (JAX).  We are seeking a Mass Spectrometry Scientist who can leverage innovative mass spec techniques, especially in the area of small molecule and metabolomics analyses, to advance JAX faculty research. Working in a high throughput, service-based facility, this position requires a high degree of independence working as a secondary interface between the facility and its users.  For more information, see https://www.jax.org/research-and-faculty/tools/scientific-research-services/formal-technologies/mass-spectrometry-and-protein-chemistry.   The Mass Spectrometry Scientist is responsible for organizing, executing, and recording benchwork and database entry for user projects, including LC/MS sample preparation, method development, operation, maintenance, data analysis, and quality control.  The duties and responsibilities include carrying out current and future techniques and SOPs of MSPC, as well as providing consultation and advice to investigators on future projects, new techniques, and applications.   
Job ID
2019-27339
Job Locations US-CT-Farmington
Posted Date 2 months ago(2/5/2020 4:55 PM)
Do you want to support the next generation of scientists? Are you excited about diversifying the face of biomedical research? We invite you to join the highly collaborative Genomic Education team in a dynamic role as Program Administrator for our on-campus education and training programs.   Help our fantastic community of students and early-career researchers thrive during their experience at JAX. Help us broaden our reach regionally, nationally, and internationally to recruit new audiences to our transformative programs.
Job ID
2019-27111
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(2/5/2020 4:42 PM)
Financial Analyst's are responsible for providing financial and analytical support to various laboratory programs including the Scientific Services.  Duties included but are not limited to working with directors/managers of these areas in developing their budgets, forecasts and financial strategic plans as well as day to day financial management of their areas and will also conduct complex cost/financial modeling analysis as needed.
Job ID
2019-27106
Job Locations US-CT-Farmington
Posted Date 2 months ago(2/4/2020 5:46 PM)
Postdoctoral position available in Multi-omics data analysis in immunology PI: Shuzhao Li, Ph.D. The Jackson Laboratory for Genomic Medicine Farmington, CT   The Li lab at The Jackson Laboratory’s Genomic Medicine campus in Farmington CT, is seeking an independent, driven PhD-level scientist (<2 years previous postdoc experience) in computational systems biology, especially in the area of integrating transcriptomics, metabolomics, proteomics, lipidomics and microbiome in immunological projects. Our goal is to model human immune system through multi-omics and multiscale data. This involves data collected from vaccine and infection studies, and from NIH data repositories. We employ statistical, data mining and machine learning approaches. The new immunometabolomics program we are building at JAX will add high-resolution chemistry into the field of systems immunology.   Qualifications: • PhD in bioinformatics, computational biology, systems biology, or other quantitative science • experience in programming language (such as Python or R) and omics data analysis. • Experience in cloud computing • Track record of productivity supported by first-author publications in peer-reviewed journals • Outstanding writing and communication skills, with an ability to work both independently and within collaborative teams productively   Candidates will be expected to apply for competitive foundation and federal training fellowships and awards. Exceptional candidates also have the opportunity to become a JAX Postdoctoral Scholar, a selective award that includes an independent research budget, travel funds, and a salary above the standard postdoctoral scale.   Interested and qualified individuals should send a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references to Dr. Shuzhao Li at shuzhao.li@gmail.com. Our research group is diverse and collaborative, and we seek to produce top notch science and foster the development of outstanding, independent scientists through critical but nurturing mentorship and interdisciplinary, collaborative efforts.
Job ID
2020-27533
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(1/31/2020 5:06 PM)
Desktop Engineer I Bar Harbor, ME   The Desktop Engineer is responsible for effective provisioning, installation/configuration, operation, and maintenance of Microsoft Windows and MacOS platforms. They will participate in technical research and development to allow for continuing innovation within the JAX organization. Desktop Engineers ensure that system hardware, operating systems, software systems, and related procedures adhere to JAX’s organizational values and IT goals.   Desktop Engineers are accountable for the following systems: Providing management support to all computers within the company. Developing and designing the company’s desktop computer strategy. Maintaining and creating OS images, packages, and patches. Maintaining all enterprise software by completing updates, security patches and installations. Resolving escalated workstation issues. This also includes software applications, tools, and lab wide projects.   Evaluates, recommends, installs, troubleshoots and maintains computers systems hardware and software to support research and business activities. Interacts with vendors in the evaluation and selection of products and with the vendors support teams to resolve technical issues. Recommends changes in procedures. Participates as a team member in IT cross-functional and Lab wide projects.
Job ID
2020-27553
Job Locations US-CT-Farmington
Posted Date 2 months ago(1/29/2020 12:49 PM)
With oversight from the Scientist of Clinical Assay Development, the Technologist II, Clinical Assay Development (CLIA) will be responsible for processing research samples using cutting-edge technologies for nucleic acid analysis, including but not limited to next-generation sequencing, Sanger sequencing, ddPCR, methylation array and associated sample preparation technologies. These activities will be performed under CLIA/CAP regulations and will directly impact human health and thus must meet the highest possible standards for quality and integrity. The Technologist I, II or III, Clinical Assay Development (CLIA) are distinguishable primarily by level of experience, supervision required, proficiency in problem solving, certification and wider range of training
Job ID
2020-27580
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(1/29/2020 9:17 AM)
There is an exciting opportunity available for a Supervisor of Operations at our Bar Harbor facility!  The Operations Supervisor is responsible for the daily oversight of all operations within their assigned area. This includes the safe operations of all equipment, the oversight of millions of dollars of fixed and consumable inventory and maintaining high standards of quality required by AALAC, ACUC and LAH.  The Operations Supervisor is responsible for all personnel actions within their assigned area to include performance, morale, discipline, training and safety.  The Operations Supervisor assures the integrity of the assigned barrier area as directed by LAH and the biosecurity program.  The Operations Supervisor is responsible for insuring their assigned staff is well informed and highly and positively motivated to reach operational goals and fulfilling the mission of The Laboratory.
Job ID
2020-27573
Job Locations US-CT-Farmington | US-ME-Bar Harbor
Posted Date 2 months ago(1/28/2020 5:26 PM)
Systems Analyst - Cloud   The Jackson Laboratory is an independent, nonprofit biomedical research institution internationally recognized for its research excellence and world-class faculty, who perform leading-edge research in the fields of human genomics and mouse genetics. At JAX, our Information Technology is as exciting and progressive as our cutting-edge science.    The Systems Analyst will plan, design, and launch efficient systems in support of scientific research in the Cloud to assist the Research IT team. The ideal candidate will have a complex and theoretical understanding and hands-on experience in Cloud environments, High Performance Computing (HPC) and scientific data management, as well as working collaboratively with researchers and Information Technology staff.
Job ID
2020-27492
Job Locations US-CT-Farmington
Posted Date 2 months ago(1/27/2020 10:57 AM)
Research Assistant III - Cell Biology Palucka Lab Farmington, CT    The incumbent will support a focused project on the immune response in the lung with work including cell culture to establish lung organoids and air-liquid cultures. Familiarity with flow cytometry and immunological assays is a plus, as these lung organoids will be used for co-cultures with dendritic cells and T cells to study the induction and regulation of immune response to respiratory viruses.  
Job ID
2020-27532
Job Locations US-CT-Farmington
Posted Date 2 months ago(1/26/2020 8:25 PM)
Postdoctoral Associate Hinson Lab     The Hinson lab is seeking an independent, highly-motivated PhD-level scientist (<2 years postdoc experience) with a strong background in cell biology to join our somatic cell genome-editing (SCGE) program funded by NIH U01 EB028898. This four-year academic project aims to: 1) interrogate human cardiac microtissues by comprehensive assessment of cardiac physiology in combination with single-cell transcriptomics to identify efficacy and adverse consequences of somatic cell genome editing targeted to heart failure-associated genetic loci, and 2) engineer autologous cardiac microtissues assembled with two distinct classes of macrophages to study cardiac function and genome editing reagents.   The Hinson lab at the Jackson Laboratory for Genomic Medicine and UConn Health studies human cardiovascular disorders especially heart failure using a combination of approaches including genome editing, pluripotent stem cell technology, genomics assays, and tissue engineering. We are a highly-collaborative multi-disciplinary team that includes expertise in genome biology, computation biology, tissue engineering and clinical cardiovascular medicine.   QUALIFICATIONS - Ph.D. in cell biology, molecular biology, genetics, or related field of study. - Prior research experience in at least two of the following areas: pluripotent stem cell biology and differentiation, cellular physiology, next-generation genome sequencing assays especially RNA-seq, and tissue engineering especially involving engineered cardiac tissues. - Experience in single cell technologies for transcriptomics, flow cytometry (or other forms of cytometric analyses), cellular histology and confocal microscopy especially live-cell imaging is particularly desirable. - Candidates should have a publication record in peer-reviewed journals. - Excellent writing and communication skills, able to work independently and effectively with other members in a productive team. - Experience with R, Python or similar statistical package is helpful, as well as experience with clustering, pathway, genetic and genomic data analyses and bioinformatics. **Please submit your current CV, at least 2 letters of reference, and 1-page (maximum) statement of Research Interests and Career Goals at time of application.**   We are a diverse and inclusive research group, aspiring to produce top science and scientists through attentive and progressive mentoring and interdisciplinary teamwork.
Job ID
2019-27084
Job Locations US-ME-Bar Harbor
Posted Date 2 months ago(1/23/2020 1:13 PM)
The Jackson Laboratory is an independent, nonprofit biomedical research institution internationally recognized for its research excellence and world-class faculty, who perform leading-edge research in the fields of human genomics and mouse genetics. At JAX, our Information Technology is as exciting and progressive as our cutting-edge science.   Reporting to the Manager of IT Applications, the Systems Engineer will work with our computational scientists, system administrators, and other Research IT staff to design, configure, and implement efficient HPC systems in support of scientific research functions and processes.
Job ID
2020-27521
Job Locations US-CT-Farmington
Posted Date 2 months ago(1/20/2020 11:26 AM)
As a Big Data Sofware Engineer come join a dynamic team and have a high impact on big data projects at the leading edge of biomedical research. The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a Senior Software Engineer for Data Engineering. This position reports to the Associate Director of Computational Sciences Scientific Computing (CSSC) team that is primarily responsible for developing software applications for scientific research programs.  This role will have a high impact on big data projects supporting research at the forefront of genetics and genomics. This is an exciting opportunity to work creatively solving tough problems with truly big data. The solutions you develop will lead to better understanding of highly complex biological systems, and support the search for cures to cancer, diabetes, Alzheimer's disease and other genetic disorders.
Job ID
2018-25477
Job Locations US-ME-Bar Harbor
Posted Date 3 months ago(1/15/2020 9:19 AM)
The Dumont Lab at The Jackson Laboratory is seeking a Postdoctoral Associate in the field of mammalian evolutionary genomics. Our group uses both wet-bench and computational tools to understand the genetic mechanisms and evolutionary processes that govern observed patterns of DNA diversity. On-going projects in the lab are investigating (i) inter-genomic conflict and sex-specific recombination rate divergence; (ii) the biological basis of sex ratio distortion; (iii) patterns, causes, and implications of mutation rate variation; and (iv) the interplay between genetic variation and chromosomal function at rapidly evolving loci like the pseudoautosomal region and centromeres. To learn more, visit this website: https://www.jax.org/research-and-faculty/faculty/beth-dumont. The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research, unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Translational research collaborations in genomics-based, personalized medicine are fostered through our JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.
Job ID
2020-27498
Job Locations US-CT-Farmington
Posted Date 3 months ago(1/14/2020 2:38 PM)
Postdoctoral Associate – Ucar Lab   We are looking for a talented and motivated individual to join Ucar Lab as a postdoctoral researcher. The Ucar Lab studies the dynamics of epigenomic regulation of gene expression in human cells and discovers predictive signatures pertaining to human aging and aging-diseases.  For more information please visit http://ucarlab.org/
Job ID
2019-26829