The Jackson Laboratory

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Job Locations US-CT-Farmington
Posted Date 2 months ago(7/15/2020 3:41 PM)
Postdoctoral Associate Christine Beck Lab   About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston in the heart of Connecticut's growing bioscience industry. Our mission at JAX-GM is to discover the complex causes of disease, develop diagnostics and therapeutics, and ultimately empower the global medical community. As a Postdoctoral Associate in the Beck laboratory, you will join a growing team of researchers focused on how the repetitive DNA content of the human genome contributes to the regulatory landscape of our genomes. We are currently seeking a postdoctoral researcher who has experience in molecular genetics work to continue an exciting project related to mobile element biology in human genomes. Experience with molecular and biochemistry is prioritized, and a willingness to learn computational techniques for genomic analyses is key for this position. The applicant needs to have a deep understanding of the biology of the human genome, and of how to frame a hypothesis. The desire to pursue interesting questions, and to find the true answers to them is paramount.   Our team consists of two graduate students, a computational scientist and a research associate. Your job would be to pursue your research, and (if possible) independent funding opportunities in this supportive and inquisitive team, and to build upon your current knowledge in a productive postdoctoral career. The position is fully funded and awaiting the proper, enthusiastic applicant.   MINIMUM QUALIFICATIONS • PhD (or nearing completion of PhD degree) • Ability to demonstrate effective productivity, presentations, and bench science adaptability. • Ability to interact with a diverse team of individuals in a productive, professional and positive manner to enhance the outcome of the goals of the research program • Established understanding of good safety practices and a demonstrated history of safe conduct • Proven ability to organize time effectively and work under time constraints, meet deadlines and prioritize work • Background and advanced knowledge in genetics • Desired techniques include mammalian cell/tissue culture, human cell culture (including ES cells) molecular cloning and verification, PCR, qPCR, and basic biochemical techniques DESIRED QUALIFICATIONS • Productivity exhibited in accepted and in press publications • Experience in library preparation for next generation sequencing • Experience with ATAC-seq, Hi-C, and ChIP-seq • Understanding and experience with computational analysis of sequencing data • Stem cell culturing experience • Mentoring experience
Job ID
2020-27846
Job Locations US-ME-Bar Harbor
Posted Date 3 months ago(6/26/2020 4:52 PM)
  The Munger Lab (mungerlab.com) is seeking a postdoctoral associate to join our growing interdisciplinary team in Bar Harbor, Maine. Our systems genetics research program explores the interface between genetics and the environment, and how complex interactions between the two can push gene regulatory networks that drive normal cell differentiation and organ development to an altered disease state. Specifically, we take advantage of powerful, genetically diverse mouse populations (Diversity Outbred and Collaborative Cross) and stem cell lines to study how genetic variation in the population impacts multiple layers of gene regulation genome-wide, with an emphasis on post-transcriptional processes that modulate protein levels independent from transcript abundance. Postdoctoral associates lead their own projects as well as participate in larger collaborative efforts involving multiple investigators, and given the current uncertainty surrounding the COVID-19 pandemic, postdocs may be expected to work remotely for a significant portion of their time. Consequently, being able to work independently and as part of a (remote) team will be essential to success in this role.    The successful candidate will integrate large genetic and multi-dimensional genomic datasets from bulk tissues down to individual cells to (1) infer the gene regulatory networks responsible for maintaining pluripotency and driving cell fate decisions; (2) identify key components of these systems that are particularly sensitive to genetic variation; and (3) define the genetic basis for cellular heterogeneity in these processes. The postdoc will take advantage of existing methods used by the lab, including quantitative trait locus mapping and mediation analysis, and will also be encouraged to develop novel computational approaches to achieve these goals. Candidates with experience at the bench will have the opportunity to validate their computational predictions with mice or cell lines in our wet lab.   The Munger Lab strives to be an open, collaborative, diverse, and supportive scientific environment, and all members of the lab are expected to do their part to achieve these goals. Dr. Munger is committed to providing post-doctoral associates and graduate students with the interdisciplinary training necessary to be successful independent scientists in the genomic era. Munger Lab members are encouraged to participate in outreach and education opportunities, and to be active citizens in their scientific and local communities.   The Jackson Laboratory (http://www.jax.org) is recognized internationally for its excellence in research, unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Translational research collaborations in genomics-based, personalized medicine are fostered through our JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.   The Jackson Laboratory provides excellent educational and training opportunities for postdoctoral associates. Exceptional candidates are encouraged to apply for the prestigious JAX Scholar award, which supports promising early-career postdoctoral associates conducting cutting edge biomedical and basic biological research at JAX. The award includes an independent research and travel budget and a salary above our standard postdoctoral scale (https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/jax-scholars.  
Job ID
2020-27809
Job Locations US-ME-Bar Harbor
Posted Date 3 months ago(6/25/2020 8:28 AM)
A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia. The Trowbridge Lab offers a challenging but supportive environment. Past trainees have a noteworthy track record for obtaining grant funding and fellowships. For more information, please visit: https://trowbridgelab.com.
Job ID
2020-27780
Job Locations US-ME-Bar Harbor
Posted Date 3 months ago(6/24/2020 4:47 PM)
The Munnamalai Lab (https://www.jax.org/research-and-faculty/research-labs/the-munnamalai-lab) at The Jackson Laboratory is seeking a postdoctoral researcher to study inner ear development. Our group identifies gene networks downstream of signaling pathways that are involved in the patterning and development of the inner ear. The inner ear is part of the peripheral nervous system. It is divided into the vestibular system that regulates balance and motion and the cochlea that regulates hearing. The cochlea has a very complex organization and we are interested in determining how a field of progenitors, under the influence of multiple signaling pathways, becomes a patterned organ with hair cells. The hair cells are mechanosensory cells of the inner ear.   The successful candidate will use molecular biology and genomic approaches to study gene regulation and cell fate determination. Applicants are not required to have experience working with mouse models; however, a strong command of molecular biology techniques is required. The postdoc will learn to use in vitro organotypic cultures, in utero electroporation, and mouse genetics to study signaling and gene regulation. The research projects involve the generation of transgenic mouse lines; generation and maintenance of mouse models of inner ear development; and characterization of molecular and cellular phenotypes of genetic mutants.   The Jackson Laboratory has a world class postdoctoral training program. Trainees are encouraged to develop an independent research program using a broad array of resources and expertise available at JAX (https://www.jax.org/research-and-faculty/tools/scientific-research-services).   Exceptional postdoctoral candidates will have the opportunity to apply to become a JAX Scholar, a selective award addressing the national need for research scientists who are accomplished in the broadly defined fields of genetics and genomics. The award includes an independent research budget, travel funds, and a salary above standard postdoctoral scale (https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/jax-scholars).   Only complete applications will be considered.  Please see submission requirements below.  
Job ID
2020-27650
Job Locations US-ME-Bar Harbor
Posted Date 3 months ago(6/24/2020 4:41 PM)
The Tarchini Lab at The Jackson Laboratory (http://tarchini-lab.org) is seeking a Postdoctoral Associate to complete a team currently composed of two postdocs, one research assistant and rotating students or shorter term trainees. The laboratory focuses on cell polarity mechanisms and their impact on the morphogenesis of sensory “hair” cells in the mouse auditory and vestibular organs, including hearing and balance ability. We are particularly interested in discovering new protein complexes organizing and elongating the stereocilia bundle, the apical hair cell compartment capturing sound or head movements. We are also interested in understanding how these proteins respond to damage, and more generally, to ask whether the molecular machinery assembling the stereocilia bundle during development could be leveraged to regenerate these structures after injury. We are independently funded with two R01 grants from NIH.   The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research (e.g., The Nathan Shock Aging Center and Center for Novel Alzheimer’s Disease Models), unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Translational research collaborations in genomics-based, personalized medicine are fostered through our JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.
Job ID
2020-27594
Job Locations US-ME-Bar Harbor
Posted Date 3 months ago(6/24/2020 2:48 PM)
The Senior Manager of Metabolic Phenotyping is experienced in the field of energy balance and glucose homeostasis with extensive expertise in phenotyping mouse models of metabolic disorders and aging. The successful candidate will provide scientific and technical leadership within the Centerfor Biometric Analysis (CBA) in mouse metabolic phenotyping for a range of biomedical domains including diabetes, obesity, tissue homeostasis, metabolic syndrome and exercise physiology. This experienced, PhD level scientist supports the strategic vision for the Jackson Laboratory’s (JAX) CBA,and has direct oversight of core facility infrastructure, staff, and operations for metabolic phenotyping. They will deliver sustained growth and development of metabolic phenotyping activities within the CBA. This scientist will be responsible for collaborating with JAX Faculty and staff at all levels including junior technical staff, postdocs and senior scientists, to provide training, consultation on experimental design, study execution, data analysis and biological interpretation. Development and implementation of new platforms and technologies, and adaptation of established phenotyping paradigms to test on wild-derived mouse strains, will be another major component of the role.
Job ID
2020-27827
Job Locations US-CT-Farmington
Posted Date 3 months ago(6/15/2020 2:44 PM)
Postdoctoral Associate Lee Lab The Lee lab is seeking a highly-motivated postdoc with strong background in bioinformatics and computational biology. The Lee Lab at the Jackson Laboratory for Genomic Medicine uses state-of-the-art technologies to study structural genomic variation in human biology, evolution and disease. Ongoing studies in the lab include: 1. accurate identification and annotation of structural variation in human and other vertebrate genomes; 2. identification and characterization of genetic aberrations associated with congenital birth defects; 3. the development of new diagnostic assays and platforms for genomic medicine; 4. understanding genome evolution in vertebrate species and its impact on genome stability
Job ID
2020-27813
Job Locations US-CT-Farmington
Posted Date 4 months ago(6/11/2020 11:31 AM)
Bioinformatics - Postdoctoral Associate Dr. Peter Robinson Lab The Jackson Laboratory   Full time position for a Bioinformatics Postdoctoral Associate to join an interdisciplinary team of computational biologists, clinicians, and ontologists who are working together to develop machine-learning and semantic algorithms for the analysis of clinical data. The position is located at the Jackson Laboratory for Genomic Medicine in Farmington, CT   We are looking for an enthusiastic individual who will take a hands-on, problem-solving approach to clinical machine-learning, collegial work environment that is infused with intellectual rigor. The right candidate will have an outstanding academic record and strong communication skills, will demonstrate innovative and analytical thinking, and will enjoy working as part of the CTSA National Center for Data to Health (CD2H; https://ctsa.ncats.nih.gov/cd2h/). The new National Center for Data to Health (CD2H), a multi-institutional consortium led by OHSU, has been awarded a $25 million grant from the National Institutes of Health to support the use of health data, algorithms and information systems to bridge basic science and clinical research and to foster collaboration across more than 50 medical research institutions within the national Clinical and Translational Science Awards network.
Job ID
2020-27646
Job Locations US-CT-Farmington
Posted Date 4 months ago(6/5/2020 2:02 PM)
SUPERVISOR OF CLINICAL VIROLOGY FULL TIME/TEMPORARY   Under the general supervision of the Clinical Laboratory Manager and/or Clinical Laboratory Director, provides assistance in planning, organizing and preparing laboratory exercises in support of the Clinical Genomics Laboratory (CGL) at JAX Genomic Medicine. A primary responsibility is to supervise laboratory personnel, overseeing clinical/production testing and troubleshooting issues if they arise. This position requires a high degree of technical abilities in molecular biology and virology. The position also requires administrative duties such as weekly laboratory updates, management of laboratory inventory, and other duties deemed necessary by the Clinical Laboratory Manager and/or Clinical Laboratory Director.   Certification: ASCP Certification in Molecular Biology
Job ID
2020-27805
Job Locations US-CT-Farmington
Posted Date 4 months ago(5/27/2020 3:25 PM)
As a full time System Engineer at The Jackson Laboratory, you'll be part of an organization whose IT technology is as exciting and progressive as our science. We are currently looking for motivated individuals who will work with our computational scientists, system administrators, and other Research IT staff to design, configure, and implement efficient research computing systems in support of scientific research functions and processes  
Job ID
2020-27521
Job Locations US-CT-Farmington
Posted Date 4 months ago(5/26/2020 12:16 PM)
Postdoctoral Research Associate (wet lab) Ruan Lab at the Jackson Laboratory for Genomic Medicine   The Ruan Lab is currently funded by two NIH center grants (4DN and ENCODE), and supported by the Roux family endowment and the JAX 3D Genome Center. Its primary mission is to develop cutting-age technologies for comprehensive mapping of 3D genome organizations in human and mouse, and to uncover the molecular mechanisms that control important genome functional modulation including gene transcription regulation. In this position within the Ruan Lab and the JAX 3D Genome Center, the incumbent will provide scientific and programmatic leadership in the strategic discussion, technological development, experimental implementation, and data analysis/ interpretation, etc. The role will involve significant interaction and collaboration within the center, the Jackson Laboratory, and with external partners, particularly within the 4DN and ENCODE consortia.  This position offers great growth opportunity to contribute both in novel technology development and advanced genomic discoveries that have immediate relevance in genetics and clinical significance in an innovative and fast-paced team environment. For more information on the Ruan Lab’s research and goals, visit: https://www.jax.org/research-and-faculty/research-labs/the-ruan-lab.   Qualifications - PhD in genomics, genetics, molecular biology, and related areas - Strong background in genomics and epigenomics, chromatin biology - Solid publication track record - Experiences with microfluidics and single cell analysis are desirable   To Apply Please send a curriculum vitae (CV) to Dr. Yijun Ruan (yijun.ruan@jax.org).
Job ID
2019-27331
Job Locations US-CT-Farmington
Posted Date 4 months ago(5/26/2020 12:15 PM)
Postdoctoral Associate – Ucar Lab   We are looking for a talented and motivated individual to join Ucar Lab as a postdoctoral researcher. The Ucar Lab studies the dynamics of epigenomic regulation of gene expression in human cells and discovers predictive signatures pertaining to human aging and aging-diseases.  For more information please visit http://ucarlab.org/
Job ID
2019-26829
Job Locations US-CT-Farmington
Posted Date 4 months ago(5/26/2020 12:15 PM)
Postdoctoral position available in Functional (epi) genomics of pancreatic islet dysfunction in type 2 diabetes PI: Michael L. Stitzel, Ph.D. The Jackson Laboratory for Genomic Medicine Farmington, CT The Stitzel lab at The Jackson Laboratory’s Genomic Medicine campus in the Hartford, CT area is seeking an independent, driven PhD-level scientist (<2 years previous postdoc experience) in integrated functional (epi)genomics and/or quantitative genetics to join our growing, externally-funded research program. Our overarching goal is to understand the genetic and cellular underpinnings of islet (dys)function and diabetes. We employ innovative (epi)genomic profiling and single cell genomic technologies, mouse models, and CRISPR/Cas9 (epi)genome editing platforms to identify key genes and pathways controlling human islet cell identity and function and to understand how diabetes-associated DNA sequence variants and environmental stimuli/stressors alter these programs to contribute to islet failure in diabetes.     Interested and qualified individuals should submit a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references at time of application. Our research group is diverse and collaborative, and we seek to produce top notch science and foster the development of outstanding, independent scientists through critical but nurturing mentorship and interdisciplinary, collaborative efforts.
Job ID
2019-27183
Job Locations US-ME-Bar Harbor
Posted Date 5 months ago(4/27/2020 1:23 PM)
The Ke Lab is seeking a postdoctoral associate at The Jackson Laboratory in Bar Harbor, Maine. The lab focuses on RNA, a central node of genetic information flow from DNA to protein. Malfunction of RNAs leads to many human diseases, including neurological diseases and cancer. To thoroughly address fundamental molecular mechanism of RNA, the Ke lab utilizes multidisciplinary approaches, including cutting-edge computational biology, biochemistry, innovative bio-technologies, genetics and molecular biology. We are especially interested in m6A RNA biology: 1) the fundamental mechanism of m6A RNA biology, and 2) the biological effects of m6A regulation in nerve system, using mouse and human iPS models. (References: 1] Ke, S. et al. m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover, Genes & Development 2017, 31: 990-1006; 2] Ke, S. et al. A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation, Genes & Development 2015, 29:2037-53.)  To learn more about the Ke Lab, please visit: https://www.jax.org/research-and-faculty/faculty/shengdong-ke.
Job ID
2018-25557
Job Locations US-CT-Farmington
Posted Date 5 months ago(4/27/2020 8:55 AM)
Postdoctoral Associate – Computational Cancer Biology Li Lab   Dr. Sheng Li’s lab at JAX-GM in Hartford, CT area is seeking a computational biology postdoctoral associate who is interested in studying cancer functional genomics. The Li Lab’s primary interests are computational biology and machine learning with a focus on functional genomics in normal and cancer systems. For additional information, visit the Li Lab online.    Key Responsibilities: -  Develop principled methods, based on machine learning and advanced statistical modeling techniques to address biological questions. -  Analyze massive functional genomics data at single cell and population levels. Requirements: - PhD in Computational Biology, or related quantitative area. - A strong background in machine learning or substantial experience analyzing large genomic datasets. - Programming experience in R, Python, or C++. - Publications in peer-reviewed journals. - Strong problem-solving skills, excellent communication skills, and enthusiastic about science.   Salary is competitive and will be supplemented with funding for computational equipment and for attending national and international conferences.    The Jackson Laboratory (JAX, www.jax.org) is a nonprofit biomedical research institute with over 2,000 employees whose mission is to discover precise genomic solutions for human disease and empower the global biomedical community in the shared quest to improve human health. A National Cancer Institute-designated Cancer Center, JAX has a mammalian genetics headquarters in Bar Harbor, Maine, a facility in Sacramento, California, and a genomic medicine facility, The Jackson Laboratory for Genomic Medicine (JAX-GM), in Farmington, Connecticut.   JAX-GM is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX-GM’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup.   JAX-GM sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories.   JAX-GM resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX-GM is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports. JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!   Our Values: INTEGRITY - Courage and commitment to do what is right PEOPLE - Inspiring our people to enhance the health of all ONE TEAM - Unified by our promise to transform medicine and science EXCELLENCE - Achieving world-class results INNOVATION - Leading with discovery and creative solutions STEWARDSHIP - Caring for and enhancing the resources entrusted to us   What do we have to offer? JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program and an onsite full service cafeteria.   Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.   The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.   Learn more about career opportunities at JAX: http://www.jax.org/careers.
Job ID
2019-27422
Job Locations US-ME-Bar Harbor
Posted Date 5 months ago(4/21/2020 11:29 AM)
The Kaczorowski Lab at The Jackson Laboratory is seeking a Postdoctoral Associate to investigate mechanisms underlying susceptibility and resilience to normal aging and Alzheimer’s disease (https://www.neuro-central.com/2018/09/19/risk-resilience-understanding-role-genetics-alzheimers-disease/).  Dr. Kaczorowski is an Associate Professor and the Evnin Family Endowed Chair in Alzheimer’s Research at the Jackson Laboratory – a research institution specializing in genetics and genomics in order to discover solutions for disease. Projects leverage novel mouse models, in vitro slice electrophysiology, circuit mapping and genome engineering to understand how genetic and environmental factors interact to influence learning and memory, cognitive aging, neurodegeneration, and Alzheimer’s. Sources of support include NIH, BrightFocus, The Glenn Foundation for Medical Research, as well as generous philanthropy awards in support of research and innovation in areas of normal aging and Alzheimer’s Disease.   Exceptional candidates will have the opportunity to apply for the prestigious JAX Scholar award, which supports promising early-career postdoctoral associates conducting cutting edge biomedical and basic biological research at JAX. The award includes an independent research and travel budget and a salary above our standard postdoctoral scale (https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/jax-scholars    
Job ID
2018-24771
Job Locations US-ME-Bar Harbor
Posted Date 8 months ago(2/11/2020 7:40 AM)
A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to study epigenetic mechanisms governing hematopoietic stem cell lineage commitment and how deregulation of epigenetic modifications leads to myeloproliferative disorders including leukemia. The Trowbridge Lab offers a challenging but supportive environment. Past trainees have a noteworthy track record for obtaining grant funding and fellowships. For more information, please visit: https://trowbridgelab.com.
Job ID
2018-25929
Job Locations US-CT-Farmington
Posted Date 9 months ago(12/30/2019 11:18 AM)
Associate Research Scientist Chuang Lab   Computational biology is critical not only to the processing and manipulation of data, but to the scientific discovery process itself. Our lab empowers computational biologists to make discoveries by providing a rich work environment for computational/mathematical analysis of biological systems, access to novel data and computational infrastructure, resources to conduct new experimental measurements, and partnerships with experimental colleagues with shared interests. As of December 2019, the Chuang Lab is seeking a scientist to join our projects combining computational and experimental approaches to study cancer. This project is being considered primarily at the level of a postdoctoral fellow, but scientists with prior postdoctoral experience and relevant expertise may be considered at the associate research scientist level upon discussion. Our current projects are at the intersections of cancer biology, machine learning, genomics, image analysis, and pathology. This is a fast-moving field with tremendous opportunities to understand cancer and impact patient outcomes. New team members will have unique opportunities to investigate mechanisms of cancer, to design new studies, and to develop novel artificial intelligence approaches to mine these data. Our lab seeks to understand how tumor ecology and evolution impact susceptibility and response to immunotherapy, targeted therapy, and chemotherapy. We interrogate these questions by generating data from clinical samples and model systems (xenografts, organoids) and by mining large cancer genomic and imaging datasets using techniques such as deep learning and evolutionary modeling. This position is supported by an R01 grant from the NCI awarded through 2023. While our lab focuses on computational approaches, we also generate our own data by making use of the extensive scientific services at JAX and in collaboration with many experimental colleagues. These include clinical and experimental groups at JAX (Robson, Palucka, Liu, Anczukow-Camarda, et al.) and with external partners (NCI PDXNet, Yale, Northwestern, UCSD, et al). We have particular access to patient-derived xenografts (PDXs) due to Prof. Chuang's position as co-PI of the National Cancer Institute's PDXNet Consortium Data Commons and Coordination Center, in addition to the extensive data and experimental resources for PDXs at JAX. Thus candidates will have novel opportunities at the intersection of data interpretation, algorithms, and experimental design. For this position, the ideal candidate will have Ph.D. experience in computational biology, cancer biology, evolutionary biology, digital pathology, or a similar discipline. Outstanding applicants new to computational biology will also be considered as the lab has an extensive record of training candidates who originally studied in other fields, including physics, applied math, computer science, electrical engineering, and experimental molecular biology. A particular area of growth for the lab is the combination of genomic and pathological analysis, and those with a medical background in pathology but a strong interest in computational approaches are encouraged to apply. Computing (programming, data analysis, statistical inference, etc), publication, and communication skills will be essential. Across these backgrounds, enthusiasm and aptitude for computational biology are what define the lab.
Job ID
2019-27442