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The Computational Sciences-Scientific Computing group is looking for a software quality assurance (SQA) lead (full/senior) with an interest in biomedical research. This is an excellent opportunity to build, expand and manage a small team of quality engineers and learn modern software testing frameworks and technologies (hands-on). This role shares equal responsibility for delivering high-quality software applications on time in collaboration with development lead and project manager, while meeting scientific goals. In addition, you would lead education of the development team in best practices in the full scope of testing and software release.
This role will have a high impact on software projects supporting research at the forefront of genetics and genomics research. This is an exciting opportunity to work creatively solving challenging problems, both in building new tools from scratch, and in developing processes for interconnecting existing scientific software applications. The solutions you develop will lead to better understanding of highly complex biological systems, and support the search for cures to cancer, diabetes, Alzheimer's disease and other genetic disorders.
*partial remote candidates must be willing to travel periodically (at least once a month) to Farmington CT or Bar Harbor ME campuses.
The Lee lab is seeking a highly-motivated postdoc with strong background in bioinformatics and computational biology. The Lee Lab at the Jackson Laboratory for Genomic Medicine uses state-of-the-art technologies to study structural genomic variation in human biology, evolution and disease. Ongoing studies in the lab include:
1. accurate identification and annotation of structural variation in human and other vertebrate genomes;
2. identification and characterization of genetic aberrations associated with ceongenital birth defects;
3. the development of new diagnostic assays and platforms for genomic medicine;
4. understanding genome evolution in vertebrate species and its impact on genome stability
Working under minimal supervision from the manager of Genome Technologies, the incumbent is responsible for testing, developing, streamlining, improving and implementing protocols (new or existing) using cutting-edge nucleic acid and library preparation, next generation sequencing (NGS) and associated technologies. The incumbent will work directly with the research and clinical labs to provide services and training. Responsibilities include testing new protocols, preparing biological samples,constructing genomic libraries and operating NGS technologies. Good knowledge in molecular biology and strong hands-on skills are critical in protocol development and implementation. Experience in automation and protocol/process scale-up highly desired, as is direct experience with operating Illumina sequencers (HiSeq, NextSeq, MiSeq) and/or PacBio Sequencers. Strong interpersonal and written and oral communications skills are required. In addition, a Technologist III will be responsible for mentoring and training other members of the lab.
Bioinformatics - Postdoctoral Associate
Dr. Peter Robinson Lab
The Jackson Laboratory
Full time position for a Bioinformatics Postdoctoral Associate to join an interdisciplinary team of computational biologists, clinicians, and ontologists who are working together to develop machine-learning and semantic algorithms for the analysis of clinical data. The position is located at the Jackson Laboratory for Genomic Medicine in Farmington, CT
We are looking for an enthusiastic individual who will take a hands-on, problem-solving approach to clinical machine-learning, collegial work environment that is infused with intellectual rigor. The right candidate will have an outstanding academic record and strong communication skills, will demonstrate innovative and analytical thinking, and will enjoy working as part of the CTSA National Center for Data to Health (CD2H; https://ctsa.ncats.nih.gov/cd2h/). The new National Center for Data to Health (CD2H), a multi-institutional consortium led by OHSU, has been awarded a $25 million grant from the National Institutes of Health to support the use of health data, algorithms and information systems to bridge basic science and clinical research and to foster collaboration across more than 50 medical research institutions within the national Clinical and Translational Science Awards network.
The Associate/Project Manager will have a solid background of theoretical and practical knowledge in the biological sciences to understand the products and services of the In Vivo Bar Harbor team. Associate/Project Managers are responsible for working with the study director and customer to define project scope, goals and deliverables and for overall project coordination, execution and completion. This position requires an in-depth understanding of operations and service deliverables, available products and services, a customer centric focus, excellent communication skills, and proficiency with available project tracking and communication tools to enable the Project Manager to ensure a positive customer experience. This position is the key responsible party to ensure that the customer’s project is on track and that internal resources are used responsibly.
SUPERVISOR OF CLINICAL VIROLOGY
Under the general supervision of the Clinical Laboratory Manager and/or Clinical Laboratory Director, provides assistance in planning, organizing and preparing laboratory exercises in support of the Clinical Genomics Laboratory (CGL) at JAX Genomic Medicine. A primary responsibility is to supervise laboratory personnel, overseeing clinical/production testing and troubleshooting issues if they arise. This position requires a high degree of technical abilities in molecular biology and virology. The position also requires administrative duties such as weekly laboratory updates, management of laboratory inventory, and other duties deemed necessary by the Clinical Laboratory Manager and/or Clinical Laboratory Director.
Certification: ASCP Certification in Molecular Biology
As a Big Data Sofware Engineer come join a dynamic team and have a high impact on big data projects at the leading edge of biomedical research.
The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a Senior Software Engineer for Data Engineering. This position reports to the Associate Director of Computational Sciences Scientific Computing (CSSC) team that is primarily responsible for developing software applications for scientific research programs.
This role will have a high impact on big data projects supporting research at the forefront of genetics and genomics. This is an exciting opportunity to work creatively solving tough problems with truly big data. The solutions you develop will lead to better understanding of highly complex biological systems, and support the search for cures to cancer, diabetes, Alzheimer's disease and other genetic disorders.
Our Physiology and Cardiac Phenotyping team focuses on identifying phenotypes in genetic models of human diseases such as cardiovascular disease, vision, hearing and brain disorders. Using the mouse as our model organism, we apply a range of gold standard and cutting edge technologies to study the phenotypic consequences of genetic manipulations. This includes cardiac ultrasound; cardiac pressure volume loop ; telemetry blood pressure, electrocardiogram (ECG) and eletroencephogram (EEG) ; electroretinogram(ERG); and auditory brainstem response (ABR) et al.
We are looking to recruit an enthusiastic and skilled Research Assistant to perform physiological characterization of mice using the above phenotyping assays. The day to day activities of the role will include schedule coordination, experimental design, developing and documenting methodology, conducting procedures, data collection, quality control and analysis, as well as assisting in the preparation of publications and reports.
CLINICAL GENOMIC TECHOLOGIST, COVID 19
Full Time, Temporary (3-6 months)
The Clinical Genomics Technologist II will be responsible for accessioning and processing COVID19 clinical samples in the Clinical Genomics Laboratory. These activities will be performed under CLIA/CAP regulations and will directly impact human health and thus must meet the highest possible standards for quality and integrity.
The Jackson Laboratory is immediately seeking a computational scientist at the level (Assistant/Associate/Full Computational Scientist) to join our Computational Sciences group. This position offers the opportunity to make leading contributions to cutting edge research in mouse genetics, disease biology, and translational research in collaboration with the faculty and genetic resource scientists and clients of The Jackson Laboratory (JAX). Cross campus and industry collaborations are encouraged.
When organizational business travel safely resumes, the Computational Scientist hire is expected to make periodic multi-day work visits to the Bar Harbor, ME campus of The Jackson Laboratory.
Systems Analyst - Cloud
The Jackson Laboratory is an independent, nonprofit biomedical research institution internationally recognized for its research excellence and world-class faculty, who perform leading-edge research in the fields of human genomics and mouse genetics. At JAX, our Information Technology is as exciting and progressive as our cutting-edge science.
The Systems Analyst will plan, design, and launch efficient systems in support of scientific research in the Cloud to assist the Research IT team. The ideal candidate will have a complex and theoretical understanding and hands-on experience in Cloud environments, High Performance Computing (HPC) and scientific data management, as well as working collaboratively with researchers and Information Technology staff.
As a full time System Engineer at The Jackson Laboratory, you'll be part of an organization whose IT technology is as exciting and progressive as our science. We are currently looking for motivated individuals who will work with our computational scientists, system administrators, and other Research IT staff to design, configure, and implement efficient research computing systems in support of scientific research functions and processes
Postdoctoral Research Associate (wet lab)
Ruan Lab at the Jackson Laboratory for Genomic Medicine
The Ruan Lab is currently funded by two NIH center grants (4DN and ENCODE), and supported by the Roux family endowment and the JAX 3D Genome Center. Its primary mission is to develop cutting-age technologies for comprehensive mapping of 3D genome organizations in human and mouse, and to uncover the molecular mechanisms that control important genome functional modulation including gene transcription regulation. In this position within the Ruan Lab and the JAX 3D Genome Center, the incumbent will provide scientific and programmatic leadership in the strategic discussion, technological development, experimental implementation, and data analysis/ interpretation, etc. The role will involve significant interaction and collaboration within the center, the Jackson Laboratory, and with external partners, particularly within the 4DN and ENCODE consortia. This position offers great growth opportunity to contribute both in novel technology development and advanced genomic discoveries that have immediate relevance in genetics and clinical significance in an innovative and fast-paced team environment. For more information on the Ruan Lab’s research and goals, visit: https://www.jax.org/research-and-faculty/research-labs/the-ruan-lab.
- PhD in genomics, genetics, molecular biology, and related areas
- Strong background in genomics and epigenomics, chromatin biology
- Solid publication track record
- Experiences with microfluidics and single cell analysis are desirable
Please send a curriculum vitae (CV) to Dr. Yijun Ruan (email@example.com).
Postdoctoral Associate – Ucar Lab
We are looking for a talented and motivated individual to join Ucar Lab as a postdoctoral researcher. The Ucar Lab studies the dynamics of epigenomic regulation of gene expression in human cells and discovers predictive signatures pertaining to human aging and aging-diseases. For more information please visit http://ucarlab.org/
Postdoctoral position available in
Functional (epi) genomics of pancreatic islet dysfunction in type 2 diabetes
PI: Michael L. Stitzel, Ph.D.
The Jackson Laboratory for Genomic Medicine
The Stitzel lab at The Jackson Laboratory’s Genomic Medicine campus in the Hartford, CT area is seeking an independent, driven PhD-level scientist (<2 years previous postdoc experience) in integrated functional (epi)genomics and/or quantitative genetics to join our growing, externally-funded research program. Our overarching goal is to understand the genetic and cellular underpinnings of islet (dys)function and diabetes. We employ innovative (epi)genomic profiling and single cell genomic technologies, mouse models, and CRISPR/Cas9 (epi)genome editing platforms to identify key genes and pathways controlling human islet cell identity and function and to understand how diabetes-associated DNA sequence variants and environmental stimuli/stressors alter these programs to contribute to islet failure in diabetes.
Interested and qualified individuals should submit a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references at time of application. Our research group is diverse and collaborative, and we seek to produce top notch science and foster the development of outstanding, independent scientists through critical but nurturing mentorship and interdisciplinary, collaborative efforts.
The Maintenance & Utility Technician position is responsible for work of complex difficulty in operation, maintenance, modification, troubleshooting, and repair of utility plant systems which include all components but not limited to high pressure & low pressure steam boilers, water boilers, chillers, cooling towers, hot & cold water systems, pumping systems, steam systems, steam traps, PRV stations, water treatment, diesel generators, and building automation system. Assists in the repair of Building Automation Systems, Fire Protection Systems, Security Systems, HVAC Systems, Lighting, Process Equipment Systems, Building Maintenance, and other tasks as they apply to demands of the department.
The Neurophysiology Specialist has expertise in establishing, implementing, and executing complex experiments using neurophysiology techniques, including EEG, EMG, and LTP and conducting data analysis and interpretation in support of Neurobehavioral phenotyping in the Center for Biometric Analysis. This is a key position within the Center for Biometric Analysis, requiring project management experience and extensive technical expertise across a multitude of complex phenotyping platforms.
You could make a difference in advancing our mission at The Jackson Laboratory as a Facilities Project Manager - Architect based at our Bar Harbor, Maine site as part of the Facilities Engineering team!
This full-time professional role will be responsible for managing capital projects from programming through close-out, with primary focus on renovations and new construction across our four campuses with budgets ranging from $20k - $20M. The successful candidate will develop project needs with clients and stakeholders and oversee designers, engineers, contractors, and other resources to assure successful delivery and closeout of each project.
Excellent opportunity to join the Facilites Team in Sacramento at The Jackson Laboratory as a Building Automation Technician! The Building Automation Technician position is responsible for work of complex difficulty in operation, maintenance ( controls, sensors), modifications, calibration, troubleshooting, and repair of Building Automation Systems, Fire Protection Systems, Security Systems and other tasks as they apply to demands of the department, including experience working with Johnson Controls. The Building Automation Technician will perform work with a greater degree of self-sufficiency and independence, be a mentor, provide guidance and will train less experienced technicians.
The Senior Manager - Business Intelligence / Data Analytics directly oversees a team of 8 IT professionals to design, plan, coordinate, implement and maintain and related application technologies tied to Business Intelligence and Data Analytics. This position will work closely with application owners, management and faculty members as a customer-oriented partner to identify, categorize and prioritize requests; to contribute to the development of project and program roadmaps, and to develop and support cost-effective technology solutions.