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The Jackson Laboratory (JAX) seeks a Discovery and Metadata Librarian to lead the Jackson Laboratory in defining and supporting the library information services in this era of data science and digital information support services. The Laboratory is a world leader in mammalian genetics and human genomics with locations in Bar Harbor, Maine; Farmington, Conn., Sacramento, Calif., and China. We also educate current and future scientists and provide critical resources, data, tools, and services to researchers worldwide. The Librarian will necessarily have an expansive role to include the skills of a biomedical librarian with the growth of the Lab in the area of genome medicine. Biomedical librarians are information specialists who aid in finding medical documents covering topics such as clinical trials, medical treatments or procedures, as well as other pertinent information that applies to the medical industry.
The Jackson Laboratory Discovery and Metadata Librarian, possessing digital librarian training and skills, will participate in the expansion of data science methods and repositories throughout the Laboratory. Jackson Laboratory researchers are deeply involved in data science and in the development and maintenance of metadata standards for biomedical data, including mouse strain and gene nomenclature, the Gene Ontology, mouse anatomy ontologies, and the Mammalian and Human Phenotype Ontologies. Libraries and librarians supporting a research institution such as the Jackson Laboratory face exciting new challenges such as the need to offer a variety of data support services: information instruction and training, data management planning guidance, stewardship, and curation. Linked data is a regular topic of discussion.
We seek a librarian and digital information resources specialist interested in participating in this new wave of change, embracing training, encouraging the transition and working broadly with the entire Jackson Laboratory Community as well as its collaborators to facilitate and embrace this change and to push the envelope of what this means to the future skills of Library and Library Data Services. The Jackson Laboratory Discovery and Metadata Librarian will be joining at an exciting time in genetics and genome sciences.
The Kaczorowski Lab at The Jackson Laboratory is seeking a Postdoctoral Associate to investigate mechanisms underlying susceptibility and resilience to normal aging and Alzheimer’s disease (https://www.neuro-central.com/2018/09/19/risk-resilience-understanding-role-genetics-alzheimers-disease/). Dr. Kaczorowski is an Associate Professor and the Evnin Family Endowed Chair in Alzheimer’s Research at the Jackson Laboratory – a research institution specializing in genetics and genomics in order to discover solutions for disease. Projects leverage novel mouse models, in vitro slice electrophysiology, circuit mapping and genome engineering to understand how genetic and environmental factors interact to influence learning and memory, cognitive aging, neurodegeneration, and Alzheimer’s. Sources of support include NIH, BrightFocus, The Glenn Foundation for Medical Research, as well as generous philanthropy awards in support of research and innovation in areas of normal aging and Alzheimer’s Disease.
Exceptional candidates will have the opportunity to apply for the prestigious JAX Scholar award, which supports promising early-career postdoctoral associates conducting cutting edge biomedical and basic biological research at JAX. The award includes an independent research and travel budget and a salary above our standard postdoctoral scale (https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/jax-scholars
The Kaczorowski Lab at The Jackson Laboratory is seeking an Associate Research Scientist to support our ongoing research program and to develop new research projects. Our group primarily focuses on mechanisms of learning and memory, as well as genetic diseases of aging (Alzheimer’s and related dementias). The successful candidate will continue and extend studies of the molecular signatures that underlie learning and memory, and disease-related pathological changes in translational models of Alzheimer’s disease. The applicant must be a team player with exceptional organizational and project management skills, including the ability to plan, schedule, and successfully carry out multiple projects at the same time. In addition to experimental studies, the applicant is expected to participate in manuscript preparation and grant writing, and will be strongly encouraged to obtain independent funding.
The Munnamalai Lab (https://www.jax.org/research-and-faculty/research-labs/the-munnamalai-lab) at The Jackson Laboratory is seeking a postdoctoral researcher to study inner ear development. Our group identifies gene networks downstream of signaling pathways that are involved in the patterning and development of the inner ear. The inner ear is part of the peripheral nervous system. It is divided into the vestibular system that regulates balance and motion and the cochlea that regulates hearing. The cochlea has a very complex organization and we are interested in determining how a field of progenitors, under the influence of multiple signaling pathways, becomes a patterned organ with hair cells. The hair cells are mechanosensory cells of the inner ear.
The successful candidate will use molecular biology and genomic approaches to study gene regulation and cell fate determination. Applicants are not required to have experience working with mouse models; however, a strong command of molecular biology techniques is required. The postdoc will learn to use in vitro organotypic cultures, in utero electroporation, and mouse genetics to study signaling and gene regulation. The research projects involve the generation of transgenic mouse lines; generation and maintenance of mouse models of inner ear development; and characterization of molecular and cellular phenotypes of genetic mutants.
The Jackson Laboratory has a world class postdoctoral training program. Trainees are encouraged to develop an independent research program using a broad array of resources and expertise available at JAX (https://www.jax.org/research-and-faculty/tools/scientific-research-services).
Exceptional postdoctoral candidates will have the opportunity to apply to become a JAX Scholar, a selective award addressing the national need for research scientists who are accomplished in the broadly defined fields of genetics and genomics. The award includes an independent research budget, travel funds, and a salary above standard postdoctoral scale (https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/jax-scholars).
Only complete applications will be considered. Please see submission requirements below.
Do you want to support the next generation of scientists? Are you excited about diversifying the face of biomedical research? We invite you to join the highly collaborative Genomic Education team in a dynamic role as Program Administrator for our on-campus education and training programs.
Help our fantastic community of students and early-career researchers thrive during their experience at JAX. Help us broaden our reach regionally, nationally, and internationally to recruit new audiences to our transformative programs.
Postdoctoral position available in metabolomics
PI: Shuzhao Li, Ph.D.
The Jackson Laboratory for Genomic Medicine
We are looking for a talented Postdoctoral associate to apply mass spectrometry based metabolomics to genomic medicine, and to develop novel methods and applications.
The ideal candidate will have a deep understanding of mass spectrometry and metabolomics, and a passion to impact biomedical research and practice. The incumbent will work closely with a team of chemists, biologists and computational scientists. The Jackson Laboratory provides unparalleled support of professional development. Metabolomics has evolved to a stage to employ rich data to guide experimental design and method development. The Li lab has recognized strengths in computational methods, integration with big data, and cutting-edge applications to human immunology and ImmunoMetabolomics. This position has the unique opportunity to interface with large scale projects on genomics, transcriptomics, microbiome, single cell technologies and cellular engineering, and to take leadership in innovations.
• Recent PhD related to metabolomics, mass spectrometry, analytical chemistry
• Experience in LC-MS, MS/MS, compound identification, isotope tracing
• Experience in Orbitrap instruments is advantageous
• Experience in metabolomics data processing and analysis
• Track record of productivity supported by first-author publications in peer-reviewed journals
• Outstanding writing and communication skills, with an ability to work both independently and within collaborative teams productively
Candidates will be encouraged to apply for competitive foundation and federal training fellowships and awards. Exceptional candidates also have the opportunity to become a JAX Postdoctoral Scholar, a selective award that includes an independent research budget, travel funds, and a salary above the standard postdoctoral scale.
Interested and qualified individuals should send a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references to Dr. Shuzhao Li at firstname.lastname@example.org.
Our research group is diverse and collaborative, and we seek to produce top notch science and foster the development of outstanding, independent scientists through critical but nurturing mentorship and interdisciplinary, collaborative efforts.
The Jackson Laboratory is a world leader in mammalian genetics, and has a mission we are passionate about: to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
The Ke Lab invites applicants for Research Assistants to join The Jackson Laboratory in Bar Harbor, Maine. The Ke Lab focuses on RNA, a central node of genetic information flow from DNA to protein (https://www.jax.org/research-and-faculty/faculty/shengdong-ke). Malfunction of RNAs leads to many human diseases, including neurological diseases and cancer. To thoroughly address fundamental molecular mechanisms of RNA, the Ke Lab utilizes multidisciplinary approaches, including cutting-edge computational biology, biochemistry, innovative bio-technologies, genetics and molecular biology.
We invite highly motivated individuals who are eager to acquire new knowledge and grow new skill sets in a team environment. Candidates with a background in one or multiple areas are preferred, including computational programming, cell culture, biochemistry, molecular biology, biotechnological method development, mouse genetics, neurosciences, immunology, stem cell, or cancer biology. The Research Assistant position offers a very exciting opportunity for junior researchers to grow their research experience and skills broadly and thoroughly. We strongly support research assistants for first-authorship/co-authorship in high quality publications, and firmly promote their professional career advancement.
The Jackson Laboratory is a world leader in mammalian genetics, and has a mission we are passionate about: to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
The Ke Lab is seeking a Research Assistant I/II/III with a quantitative computational biology background to join The Jackson Laboratory in Bar Harbor, Maine. The Ke Lab focuses on RNA, a central node of genetic information flow from DNA to protein (https://www.jax.org/research-and-faculty/faculty/shengdong-ke). Malfunction of RNAs leads to many human diseases, including neurological diseases and cancer. To thoroughly address fundamental molecular mechanisms of RNA, the Ke Lab utilizes multidisciplinary approaches, including cutting-edge computational biology, biochemistry, innovative biotechnologies, genetics, and molecular biology. The primary duties of this exciting opportunity include developing and applying cutting edge computational/statistical methods to analyze large-scale biological data, including but not limited to gene expression by RNA-seq, CLIP data, CHIP data, DNA methylation, and proteomics. The successful candidate will participate in experimental design, develop and apply analysis tools, and conduct reproducible research procedures. Preference will be given to applicants with proficiency in Python, Perl, or R programming languages.
We invite applications from highly motivated individuals who are eager to acquire new knowledge and grow new skill sets in a team environment. The research assistant position offers opportunities for junior researchers to grow their research experience and skills broadly and thoroughly.
Bioinformatics - Postdoctoral Associate
Dr. Peter Robinson Lab
The Jackson Laboratory
Full time position for a Bioinformatics Postdoctoral Associate to join an interdisciplinary team of computational biologists, clinicians, and ontologists who are working together to develop machine-learning and semantic algorithms for the analysis of clinical data. The position is located at the Jackson Laboratory for Genomic Medicine in Farmington, CT
We are looking for an enthusiastic individual who will take a hands-on, problem-solving approach to clinical machine-learning, collegial work environment that is infused with intellectual rigor. The right candidate will have an outstanding academic record and strong communication skills, will demonstrate innovative and analytical thinking, and will enjoy working as part of the CTSA National Center for Data to Health (CD2H; https://ctsa.ncats.nih.gov/cd2h/). The new National Center for Data to Health (CD2H), a multi-institutional consortium led by OHSU, has been awarded a $25 million grant from the National Institutes of Health to support the use of health data, algorithms and information systems to bridge basic science and clinical research and to foster collaboration across more than 50 medical research institutions within the national Clinical and Translational Science Awards network.
VARIANT ASSAY INTERPRETATION SCIENTIST
Clinical Scientific Curator
The Clinical Scientific Curator for the Clinical Genomics and Genetics Services unit at The Jackson Laboratory for Genomic Medicine will critically evaluate and interpret cancer genomic variants from curation into the JAX Clinical Knowledgebase (CKB). The Clinical Scientific Curator will assimilate and integrate data from scientific literature related to pathogenicity and predictive efficacy in a format compatible with clinical reporting. The Content Curator will also perform wet lab work related to Clinical Genomics activities, and will assist in quality assurance and quality control of all data within CKB.
The Jackson Laboratory has an excellent opportunity for a Study Director in Northern California....Join one of the nation's oldest biomedical research institutions and help contribute to our mission of improving lives through discovering precise genomic solutions for human disease.
Study Directors have ultimate accountability for ensuring studies are executed to the specifications of the client outlined in a scope of work, meeting or exceeding client expectations without deviation and on a specific budget. The incumbent is responsible for mentoring Project Manager(s), Senior Project Manager(s), and a team of technicians tasked with executing scientific studies on behalf of external or internal customers in a collaborative in vivo laboratory environment. In addition, the incumbent will ensure accuracy in: quoting, revenue forecasting and invoicing of the studies. The incumbent is responsible for depositing normative data from mouse models into the public domain via the Mouse Phenome Database, publications and conference presentations.
An Associate project manager is responsible for understanding and implementing complex research goals in the confines of time and budget. This is accomplished by coordinating a vast array of research services available and using best practice of project management. The ideal candidate will have a firm foundation of scientific understanding, associated with the use of mouse models of human disease, model generation and/or in vivo pharmacology. This fast pace position requires excellent organizational and communication skills, along with the ability to think critically and recommend best solutions to meet project goals.
Exciting opportunity to join the In Vivo Services team in Sacramento, CA! Working under general supervision, the In vivo Technologist will be responsible for supporting studies assigned to the Sacramento team by consistently executing procedures according to protocol and associated SOPs. This individual will be a collaborative member of the cross functional In Vivo department and may be assigned to assist the Innovation Product Development team.
Clinical Genomic Analyst II
The Clinical Genomic Analyst will contribute to clinical operations and clinical product development at The Jackson Laboratory for Genomic Medicine by working closely with CG Scientists, management and the Clinical Laboratory Director (CLD). This role will support production by performing essential data analysis, processing and reporting functions in a CLIA/CAP accredited laboratory. The Clinical Genomic Analyst role involves analysis, classification and interpretation of cancer genomic variants using scientific literature as well as genomic databases. The ideal candidate for the Clinical Genomic Analyst role at JAX will demonstrate working knowledge across many fields including bioinformatics, computational sciences, clinical laboratory sciences and genetic pathology. This position is for an individual who understands the different components of a genetic test and has the experience/exposure in clinical genetic testing environment.
Located in beautiful Bar Harbor, Maine, The Jackson Laboratory is a leading global genetics research institute that is growing and seeking talented individuals to join the team!
We are currently seeking a Product Owner reporting to the Manager of the JAX Mice and Clinical Research Services (JMCRS) Solutions Team. This unique team, positioned in the heart of the business, drives creation of efficient, effective software-based workflow solutions. Solutions encompass multiple, diverse, and complex applications supporting the business, including Microsoft Dynamics AX2009, Microsoft D365, Salesforce, Platform for Science, Sitecore, and others. This position serves as a liaison between business stakeholders and the IT scrum team and is responsible for defining the vision and value of the product to maximize the value of the work produced by IT. The Product Owner is responsible for managing the Product Backlog.
The Churchill Lab is seeking a Bioinformatics Analyst to join our research (50%) and education/training (50%) efforts in Bar Harbor, Maine. The Churchill Lab applies a systems approach to study the genetics of health and disease, incorporating new statistical methods for the investigation of complex disease-related traits in the mouse ( http://churchill-lab.jax.org/website/ ). We employ a combination of strategies to investigate the genetic basis of these complex traits. The Churchill Lab has a longstanding and successful tradition of educating the next generation of researchers and is integral to a growing bioinformatics training program in JAX Genomic Education. We employ evidence-based teaching methods promoted by The Carpentries, an international organization with a mission to train researchers in best practices for data science and computing.
We invite applications from highly motivated individuals who are eager to acquire new knowledge and grow new skill sets in a team environment. Candidates with a background in statistics or genetics are preferred. The Bioinformatics Analyst position offers an exciting opportunity for junior researchers to grow their research experience and skills broadly and thoroughly in both research and teaching. We firmly promote their professional career advancement.
The Necropsy Service has an opening for a full-time position at the Necropsy Technologist I level for our Bar Harbor, ME location!
The Necropsy Technologist will be a collaborative member of a team responsible for supporting JAX internal research programs, requesting necropsy services. Included in these responsibilities is communicating with researchers to understand their project requirements and to develop a standard protocol for their request. The Necropsy Technologist will be able to independently perform requested tissue collections and preparative procedures. This position will also provide training sessions for JAX researchers to teach necropsy, anatomy, dissections and tissue collections.
The Necropsy Technologist will also participate in routine laboratory maintenance (preparing solutions, ensuring workstation and laboratory cleanliness) and perform routine administrative tasks (project documentation, contribute to monthly billing, and ordering supplies).
The position requires a highly motivated individual with a passion for learning and teaching, who works well in a fast paced, deadline-driven environment. Ability to follow established routine procedures and defined schedules, keep records, and work in a team is critical.
The Carter Lab is seeking a postdoctoral associate to join our research in the computational genetics and genomics of complex disease (50% effort) and fill a critical role in our training efforts for the next generation of researchers (50% effort). Our work uses novel, genetically diverse mouse models to understand how genetic factors predispose to disease. We are part of the MODEL-AD consortium (model-ad.org) to create and characterize new Alzheimer’s disease models and the OPEN-AD center to translate ’omics data into potential therapeutics. In addition, we are engaged with a growing bioinformatics training program in JAX Genomic Education to teach researchers in designing experiments and analyzing data with advanced mouse models. We employ evidence-based teaching methods promoted by The Carpentries, an international organization with a mission to train researchers in best practices for data science and computing. For more information about our research, please visit: https://www.jax.org/research-and-faculty/research-labs/the-carter-lab.
The Jackson Laboratory provides excellent educational and training opportunities for postdoctoral associates. Exceptional candidates are encouraged to apply for the prestigious JAX Scholar award, which supports promising early-career postdoctoral associates conducting cutting edge biomedical and basic biological research at JAX. The award includes an independent research and travel budget and a salary above our standard postdoctoral scale (https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/jax-scholars.
This is an exciting opportunity on the Security team at our Sacramento, CA location. This position is responsible for ensuring the safety of all employees, visitors, contractors and guests as well as protecting all property and assets of The Jackson Laboratory. Responsible for staffing and monitoring at assigned post/stations and the Security Operation Center as well performing patrol rounds as assigned and necessary. This individual will respond to emergencies as necessary and providing assistance as needed. Security Services provides 24/7 coverage at The Jackson Laboratory and shift hours may include day/evening/overnight and weekend/holiday hours as required.
Scientific Software Engineer (Associate/Full/Senior)
Data Science Focus
Come join the development team of the JAX Clinical Knowledgebase (CKB). CKB is a dynamic digital resource for interpreting complex cancer genomic profiles and is used by clinicians and researchers from around the world to connect cancer variants to therapies and clinical trials. Come be a part of the fight against Cancer!
This position is available immediately for a Scientific Software Engineer (Associate/Full/Senior) with a large focus on data science, as a part of the Computational Sciences Scientific Computing group at The Jackson Laboratory for Genomic Medicine in Farmington, CT. Play a pivotal role in investigating potential integration opportunities as well as helping to lead the effort to translate those opportunities into mature software solutions. Use your skills to propose, analyze, prototype new solutions as well as run novel analysis over the existing systems. Leverage NLP, ML and AI to develop novel approaches to help streamline curation as well as add additional value to existing data. This is an exciting opportunity to work on challenging problems at the interface of biology, computer science and data science. CKB is a leading cancer knowledgebase, with partners around the world integrating CKB data, join the team and help push CKB to the next level.