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The Microinjectionist performs the processes necessary for successful microinjection and supporting surgical techniques in the Genetic Engineering Technologies (GET) team.
This position has a significant and positive impact on the GET team’s scientific capabilities, their ability to reduce costs, increase throughput and improve service quality.
POSITIONS: Scientist, Monoclonal Antobody Services
ADDRESS OF EMPLOYMENT: Bar Harbor, ME 04609
The Jackson Laboratory seeks a Scientist, Monoclonal Antibody Services to work in Bar Harbor, Maine. The Scientist, Monoclonal Antibody Services The JAX Monoclonal Antibody (MAB) service core is a high-throughput automated tissue culture and screening Method Monoclonal Antibody (MAB) facility. The JAX MAB service core produces a series of MAB affinity reagents that bind to target molecules in order to identify, track, capture, or influence specific molecular activity. The Scientist, Monoclonal Antibody Services manages and oversees the JAX MAB service core for research and reagent development.
Lee Lab Cell Biology Internship
We are seeking a highly motivated individual to join the Lee Lab research team as a 2020 summer intern. This position is accountable for performing the basic laboratory and/or related support tasks for canine induced pluripotency stem cell (iPSC) project at Dr. Charles Lee’s Lab at the Jackson Laboratory for Genomic Medicine located at Farmington, CT. Dogs and humans have many inherited genetic diseases in common and conditions that are increasingly prevalent in humans also occur naturally in dogs. The use of dogs for the experimental and clinical testing of stem cell and regenerative medicine products would benefit canine health and welfare and provide relevant animal models for the translation of therapies to the human field. The project focus is to establish canine iPSC cell lines for disease modeling.
About Your JAX Internship Experience
Join peers selected from educational institutions across the country for a summer of professional growth and career exploration. As a JAX Intern you will receive a dedicated mentor in your department and connect with your fellow interns through JAX-sponsored activities.
The intern will be involved in the procedure of deviating and characterizing canine iPSC cell lines. The candidate will be trained to design, optimize, and execute experiments under the supervision of experienced colleagues.
- Daily maintenance of tissue culture
- Perform characterization experiements such as DNA, RNA isolation, RT-PCR, immunocytochemistry staining et al. with well recorded experiment notes
- Isolation of peripheral blood mononuclear cell, skin fibroblast cells, bone marrow cells et al.
- Perform basic lab maintenance
- Reagent/solution preparation
- Development of basic and advanced skills of tissue culture and molecular characterization experiments, especially in iPSC deriviation and maintenance procedure
- Other routine wet lab techniques in a cell biology lab
- Knowleadge of the features, derivatiion, maintenance, differentiation and characterization of pluripotency stem cells
- Knowleadge and skills of of iPSC based disease modeding
JAX encourages application from a diverse mix of educational experiences and backgrounds. Preferred qualifications include:
- Basic knowledge of research protocols, principles and procedures
- Basic skills of scientific techniques such as tissue culturing, reagent/solution preparation, staining, PCR etc.
- Basic knowledge of experimental design, mathematics, statistics, computer applications, laboratory equipment and procedures
- Basic knowledge of a science such as; chemistry, biology, microbiology, pharmacology
- Basic knowledge of physical and data resources in application scientific disciplines
- Oral and written communication skills
- Ability to identify, produce, organize, analyze, evaluate and interpret data
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,300 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
Employment will require successful completion of references, background check, and pre-employment physical.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Learn more about career opportunities at JAX: http://www.jax.org/careers.
The Genome Technologies team has an exciting opening for a Genomic Technologist. This individual is responsible for testing, developing, streamlining, improving and implementing protocols (new or existing) using cutting-edge nucleic acid and library preparation, next generation sequencing (NGS) and associated technologies. The Genomic Technologist will work directly with the research and clinical labs to provide services and training.
The Protein Production and Purification (P3) Service seeks a Research Technician/Technologist to join a new service assisting JAX scientists by the cloning, expression and purification of proteins to be used as antigens and reagents at the Jackson Laboratory in Bar Harbor, Maine. Projects include a combination of mammalian cell culture, chromatography, protein analysis methods, molecular biology, Routine maintenance responsibilities. Although previous experience in these methods is preferred, a candidate with a proven track record of focus, organization, and the ability to follow SOPs while maintaining meticulous records will be considered. This position is a great opportunity for both experienced associates to expand their skills and for energetic new graduates with a passion for research. The salary will be commensurate with experience.
This position is responsible for a wide range of administrative tasks and special projects in support of members of the Clinical Genomics Team, including the Clinical KnowledgeBase (CKB), reporting to the Senior Director, Product Innovation & Commercialization. The successful candidate will join a team dedicated to providing the highest quality services and data for research and clinical applications.
The dynamic nature of this work environment requires that the ideal candidate have exemplary time management skills, be comfortable under deadlines, proficient in all Microsoft Office products, able to work in a database, strong writing skills for all correspondence and the ability to identify and anticipate highly varied needs. To perform this job successfully an individual must be able to confidentially handle highly sensitive information while exercising professional discretion. To learn more about this group at JAX, visit: https://www.jax.org/clinical-genomics.
Reporting to the JAX® Mice, Clinical & Research Services (JMCRS) Creative & UX Strategy Lead and taking significant direction from the Senior Marketing Manager and Content Manager, the Digital Designer translates business goals and initiatives into compelling, innovative, and clear digital and motion communications. The Digital Designer will need to be driven to identify and deliver good creative digital design assets, working with the design team to expand and build upon creative concepts and ideas. The Digital Designer will have excellent and current creative and design trend knowledge and skills (from branding identity and package design, digital, to time-based media).
The Digital Designer is able to problem solve and must be a team player with strong interpersonal and communication skills who is highly organized with ability to be flexible and adapt to changing priorities. This individual should be comfortable owning projects from start to finish as well as providing direction and guidance to other designers.
The Digital Designer will collaborate across JAX, working closely with Strategic Communications and JAX Creative to bring our brand to life using graphic design, typography and digital/interactive design. The ideal candidate thrives in high-pressure, fast-paced environments and can manage competing priorities to execute and deliver high-quality work to our customers. This individual is self-motivated, takes challenges head on and explores multiple solutions to every problem
This position will be an integral part of the JMCRS Marketing team, tasked with providing top-notch marketing solutions that enhance and support the Laboratory’s strategic priorities. Requires independent, creative thinking within the context of established brand standards, willingness to take and measure calculated risks, and operate in a customer-focused environment. Position will have interaction with staff at all levels of the institution, as well as external partners and constituents.
The Munnamalai Lab (https://www.jax.org/research-and-faculty/research-labs/the-munnamalai-lab) at The Jackson Laboratory is seeking a postdoctoral researcher to study inner ear development. Our group identifies gene networks downstream of signaling pathways that are involved in the patterning and development of the inner ear. The inner ear is part of the peripheral nervous system. It is divided into the vestibular system that regulates balance and motion and the cochlea that regulates hearing. The cochlea has a very complex organization and we are interested in determining how a field of progenitors, under the influence of multiple signaling pathways, becomes a patterned organ with hair cells. The hair cells are mechanosensory cells of the inner ear.
The postdoctoral associate will work on projects using in vitro organotypic cultures and mouse genetics to study signaling and gene regulation. The research projects involve the generation of transgenic cell lines using CRISPR; generation and maintenance of mouse models of inner ear development and deafness; and characterization of molecular and cellular phenotypes of genetic mutants.
The Jackson Laboratory provides excellent educational and training opportunities for postdoctoral associates. Exceptional candidates are encouraged to apply for the prestigious JAX Scholar award, which supports promising early-career postdoctoral associates conducting cutting edge biomedical and basic biological research at JAX. The award includes an independent research and travel budget and a salary above our standard postdoctoral scale (https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/jax-scholars
Only complete applications will be considered. Please see submission requirements below.
The Tarchini Lab at The Jackson Laboratory (http://tarchini-lab.org) is seeking a Postdoctoral Associate to complete a team currently composed of two postdocs, one research assistant and rotating students or shorter term trainees. The laboratory focuses on cell polarity mechanisms and their impact on the morphogenesis of sensory “hair” cells in the mouse auditory and vestibular organs, including hearing and balance ability. We are particularly interested in discovering new protein complexes organizing and elongating the stereocilia bundle, the apical hair cell compartment capturing sound or head movements. We are also interested in understanding how these proteins respond to damage, and more generally, to ask whether the molecular machinery assembling the stereocilia bundle during development could be leveraged to regenerate these structures after injury. We are independently funded with two R01 grants from NIH.
The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research (e.g., The Nathan Shock Aging Center and Center for Novel Alzheimer’s Disease Models), unparalleled mouse resources, outstanding training environment characterized by scientific collaboration, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. Translational research collaborations in genomics-based, personalized medicine are fostered through our JAX Genomic Medicine campus in Farmington, CT. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.
Located in beautiful Bar Harbor, Maine, The Jackson Laboratory is a leading global genetics research institute that is growing and seeking talented individuals to join the team!
The Jackson Laboratory is currently seeking a Business Process and Application Analyst reporting to the manager of the JAX Mice and Clinical Research Services (JMCRS) Project Support Team. This team supports Microsoft Dynamics AX2009/D365, SalesForce, their supported Data Warehouse and related operational systems such as NewVoiceMedia. The role provides key operational and project coordination across JMCRS, actively seeking to understand operational challenges and then work closely with system users and IT staff to develop, test, train and support real, functional solutions.
We are looking for a student intern to design, test and optimize custom devices for life science research. The intern will be supervised by an experienced biomedical engineer in the Schomer Lab (sponsored by the Lau Lab) at Farmington, CT. The position requires basic understanding in electronics and some experience in assembling small devices; for example, if you can follow a manual and assemble a remote-controlled toy car or drone, you will be able to complete the tasks. Some custom design and optimization will be carried out by the intern; therefore, independent thinking, attention to details and a high standardard for quality are required. The intern will have the opportunity to interact with researchers in genomic medicine and cancer biology in an enriched learning environment. This position is well suited for a biomedical engineering student with interests in next-generateion life science research.
The intern will learn how to set up and optimize small laboratory devices for specific biomedical applications. The intern will also develop skills in biomaterial and cell-material interface design and engineering. Successful completion of the tasks that lead to novel findings of cell behavior will entitle co-authorship for scientific publications.
Summer Intern - Building Automation Technician
The Jackson Laboratory is seeking a candidate for a hands on Maintenance internship with the Building Automation Systems Team in Bar Harbor and Ellsworth, Maine. This position will support the maintenance and operation of digital controls for HVAC systems, Fire Alarm & Detection, Access Control and Video Surveilance System!
Associate/Full Computational Scientist
Structural Variation (SV)
The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a Computational Scientist to join the Lee laboratory; this is an opportunity to be involved in the use of state-of-the-art technologies to study the structural genomic variation in human biology, evolution and disease.
The Computational Scientist will work closely with a team of scientists involved in the ongoing studies which includes; accurate identification and characterization of structural variation (SV) in human and other vertebrate genomes, the development of new algorithm/approach for SV detection, and understanding genome evolution in vertebrate species and its impact on genome stability.
In addition, the Computational Scientist will be involved in exciting research programs analyzing large numbers of human genomes, activities, consortium activities, and collaborations as assigned by the PI of the lab to the extent assigned. They work closely, and are not limited to, helping interns, post-doctoral fellows, scientists and grant writing. Furthermore, they will present results to others, and have many interactions at national and international conferences and workshops.
Postdoctoral position available in
Functional (epi) genomics of pancreatic islet dysfunction in type 2 diabetes
PI: Michael L. Stitzel, Ph.D.
The Jackson Laboratory for Genomic Medicine
The Stitzel lab at The Jackson Laboratory’s Genomic Medicine campus in the Hartford, CT area is seeking an independent, driven PhD-level scientist (<2 years previous postdoc experience) in integrated functional (epi)genomics and/or quantitative genetics to join our growing, externally-funded research program. Our overarching goal is to understand the genetic and cellular underpinnings of islet (dys)function and diabetes. We employ innovative (epi)genomic profiling and single cell genomic technologies, mouse models, and CRISPR/Cas9 (epi)genome editing platforms to identify key genes and pathways controlling human islet cell identity and function and to understand how diabetes-associated DNA sequence variants and environmental stimuli/stressors alter these programs to contribute to islet failure in diabetes.
Interested and qualified individuals should submit a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references at time of application. Our research group is diverse and collaborative, and we seek to produce top notch science and foster the development of outstanding, independent scientists through critical but nurturing mentorship and interdisciplinary, collaborative efforts.
The Palucka Lab at JAX-GM is currently seeking motivated scientists interested in analyzing and integrating RNA-seq, ATAC-seq, and genetic data. Additional tasks will include pre-processing of raw sequencing files, as well as more advanced integrative models using machine learning algorithms.
In addition, JAX Postdoctoral Associates benefit from:
• Research training and mentorship from award-winning faculty
• Individualized career advising and a dedicated Postdoc Program Office
• Superior scientific services and unparalleled mouse resources
• A uniquely collaborative academic research environment
• Guidance from JAX's Postdoctoral Training Committee to help you succeed
• Professional skills workshops including JAX's holistic The Whole Scientist course
• Free access to JAX’s world-renowned Courses & Conferences programs
• Outstanding benefits and salary compensation above the NIH scale
• Generous relocation assistance and free on-campus parking
The Jackson Laboratory currently has full time opportunities in their Customer Service Department for Customer Service Representatives for our Sacramento, CA facility! This role serves as the customer advocate while providing exceptional support service by timely responding to communications from customers concerning orders, product availability and relaying prices of JAX® Mice and related products as well as accurately entering orders into our order processing system. Requirements also include outbound calling initiatives and efficiently resolving customer concerns and demonstration of excellent problem solving skills. Candidates must be self-starters with a high level of initiative with the ability to multi-task effectively. They must have strong interpersonal and teamwork skills with a positive “can do” attitude and customer-centric outlook. The standard work schedule for this position will be scheduled for 40 hours, Monday through Friday, between the core hours of 8am-5pm.
The Senior Manager, Financial Planning & Analysis (FP&A) will oversee the process of compiling and analyzing The Jackson Laboratory’s long-term financial strategy. Essential tasks include but are not limited to: maintaining a multi-year financial planning model, analyze financial trends and evaluate the impact of expanded services including new research, clinical and other initiatives conducting complex cost/financial modeling analysis. The position will provide critical financial analysis and strategic planning support.
POSITIONS: Application Architect (Multiple Positions)
ADDRESS OF EMPLOYMENT: Bar Harbor, ME 04609
Great opportunity to work with our Pathology Services as a Necropsy Technician in our Bar Harbor location!
The Necropsy Technician is responsible for performing tasks associated with mouse necropsy procedures for JMCRS, including conducting necropsies on mice for diagnostic purposes for the Sick Mouse Program, for the purpose of tissue collection for external customer orders, and collecting tissues for research studies or for biorepository. The Necropsy Technician will also participate in routine laboratory maintenance (preparing solutions, ensuring workstation and laboratory cleanliness) and routine administrative tasks (monthly billing, ordering supplies).
The Jackson Laboratory is immediately seeking a Computational Scientist at the level (Assistant/Associate/Full Computational Scientist) to join our Computational Sciences group. This position offers the opportunity to make leading contributions to cutting edge research in mouse genetics, disease biology, and translational research in collaboration with the faculty and genetic resource scientists and clients of The Jackson Laboratory (JAX). Cross campus and industry collaborations are encouraged.
This position is available in Farmington, CT. The Computational Scientist hire is expected to make periodic multi-day work visits to the Bar Harbor campus of The Jackson Laboratory.