The Lee lab is seeking a highly-motivated postdoc with strong background in bioinformatics and computational biology. The Lee Lab at the Jackson Laboratory for Genomic Medicine uses state-of-the-art technologies to study structural genomic variation in human biology, evolution and disease. Ongoing studies in the lab include:
1. accurate identification and annotation of structural variation in human and other vertebrate genomes;
2. identification and characterization of genetic aberrations associated with ceongenital birth defects;
3. the development of new diagnostic assays and platforms for genomic medicine;
4. understanding genome evolution in vertebrate species and its impact on genome stability
• Algorithm development for genomic structural variation analysis on short and long read sequencing data
• Development of robust software to implement the novel algorithms
• Comparison of algorithm performance on biological datasets from JAX and other groups, participation in scientific projects within the Lee group on relevant genomics topics
• Presentation of results at scientific meetings and participation in manuscript and grant writing
• Creativity and eagerness to learn new technologies and science
• Enthusiasm for working in a dynamic, high-performance research team environment
• Strong communication skills
• PhD in bioinformatics/computational biology/computer science or similar area of study
• Background in human genetics/genomics and disease research
• Solid publication track record
• Skills in computer programming using compiled languages such as C/C++ or Java, and at least one scripting language such as Perl, Python, or bash
• Familiarity with large datasets from big consortium projects such as TCGA/ICGC/ENCODE and 1000 Genomes
• Track record of developing algorithms and tools in the area of genome variation and/or cancer biology
• Experience with analysis/method development of/for data from third generation sequencing platforms (Pacbio / 10X Genomics / Oxford Nanopore) preferred
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,300 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup.
JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories.
In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
INTEGRITY - Courage and commitment to do what is right
PEOPLE - Inspiring our people to enhance the health of all
ONE TEAM - Unified by our promise to transform medicine and science
EXCELLENCE - Achieving world-class results
INNOVATION - Leading with discovery and creative solutions
STEWARDSHIP - Caring for and enhancing the resources entrusted to us
What do we have to offer?
JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program and an onsite full service cafeteria.
Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.
Employment will require successful completion of references, background check, credit check, pre-employment physical, drug test and an appropriate non-compete agreement.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Learn more about career opportunities at JAX: http://www.jax.org/careers.