The Diagnostic Laboratory at The Jackson Laboratory assures the health and well-being of our animal colonies by routine health monitoring for undesirable infectious agents. Our diagnostic program serves to monitor against potential disease outbreaks in the Production, Research, and Repository colonies, as well as verifying the health status of foster mothers used for rederivation of mouse strains by Reproductive Sciences. The Diagnostic Laboratory also performs environmental monitoring via microbiologic culture of mouse room swabs. This testing strategy includes necropsy, serology, microbiology, and parasitology. The Genetic Quality Control (GQC) Laboratory at The Jackson Laboratory serves to detect and eliminate contamination in the genetic background of all of our Production and Repository colonies by routine and investigative screening using a panel of molecular assays.
This role is crucial to the effective functioning of the Diagnostic & GQC laboratories. The work schedule for the GQC Technician is established based on operational demands and may fluctuate based on the changing needs of the two laboratories, and thus Technicians may be assigned to any of the testing areas (Necropsy, Serology, Microbiology, Parasitology, and GQC) as necessary.
The Diagnostic & GQC Technician works under general supervision, follows standard operating procedures and protocols, and maintains lab inventory by ordering supplies as needed. The Diagnostic & GQC Technician utilizes strong analytical and problem-solving skills and attention to detail to perform complex microbiological testing and molecular assays. The Diagnostic & GQC Technician is capable of trouble-shooting and identifying common problems and issues and assisting supervisor with their resolution.
Complete necropsy involves the visual observation of all the organs, a description of any lesions seen, and the use of proper necropsy procedures. Selection of abnormal tissues for histopathology, which includes trimming of tissues and submitting the tissues and appropriate paperwork to histology. Use of aseptic techniques for the procurement of tissue samples for microbiological testing, for molecular testing, and for parasitology. Obtain blood samples from caudal venous and arterial sites or cardiac puncture for serological evaluation.
Perform parasitological examinations for ectoparasites with the use of a dissecting stereoscope. Parasitological examinations for endoparasites are done visually and microscopically. Further, perform specialized testing (fecal floatations, tape tests, etc) as required.
Performance of Luminex, ELISA and IFA procedures. This involves dilution of samples, preparation of reagents, performance of the assay, operation and maintenance of sophisticated instrumentation, and interpretation of results.
Preparation and quality control of microbiological media and chemical solutions. Further, this involves performance of subcultures, setting up biochemical identification testing for microbes, operation and maintenance of sophisticated instrumentation, and performance of other microbiological assays as required.
Digestion of routine tissue samples for extraction/purification of DNA when applicable, and coordination of outsourcing SNP assays for the purpose of monitoring genetic background. May be required to perform nucleic acid assays in house. This includes processing of samples as necessary and analysis, interpretation, and reporting of GQC results.
Performs data entry in database used for animal health & genetic quality. May be required to produce standard and ad hoc reports required including, but not limited to, reports used for shipment of animals, utlized by veterinarians, investigators, and production managers.
Miscellaneous lab work:
Duties necessary for the processing of incoming samples and for maintenance of the laboratory, such as culturing uterus / placentas from Importation, filtration and culture of water for microbiological evaluation, dilution and inoculation of anaerobic specimens, and other samples that are submitted for testing. Logging autoclave monitoring data, proper disposal of biohazardous materials, operation of autoclave, preparation of buffers, etc. Sanitation of the laboratory areas including decontamination of biohazardous waste containers/areas as well as sweeping and mopping floors on a routine schedule.
Please submit a cover letter of interest and resume!
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,300 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
The JAX® Mice, Clinical and Research Services facility is located in Sacramento, the state capital of California. Sacramento is less than a two-hour drive from San Francisco, Napa Valley, and scenic Lake Tahoe, and a short flight to both Los Angeles and Orange County. Sacramento is the birthplace of the nation’s Farm to Fork movement, and offers excellent restaurants, gastro-pubs, wineries, theaters, and museums. Outdoor activities are plentiful: Boating, white water rafting, and riding the scenic bicycle trails are popular. Housing and other costs of living are more affordable in Sacramento and its surrounding suburbs than in most other neighboring areas in the North Bay, making Sacramento one of the hottest housing markets in the country year after year.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
INTEGRITY - Courage and commitment to do what is right
PEOPLE - Inspiring our people to enhance the health of all
ONE TEAM - Unified by our promise to transform medicine and science
EXCELLENCE - Achieving world-class results
INNOVATION - Leading with discovery and creative solutions
STEWARDSHIP - Caring for and enhancing the resources entrusted to us
What do we have to offer?
JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program available to employees and their families.
Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.
Employment will require successful completion of references, background check, pre-employment physical, and drug test.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Learn more about career opportunities at JAX: http://www.jax.org/careers.