Postdoctoral position available in
Functional (epi) genomics of pancreatic islet dysfunction in type 2 diabetes
PI: Michael L. Stitzel, Ph.D.
The Jackson Laboratory for Genomic Medicine
The Stitzel lab at The Jackson Laboratory’s Genomic Medicine campus in the Hartford, CT area is seeking an independent, driven PhD-level scientist (<2 years previous postdoc experience) in integrated functional (epi)genomics and/or quantitative genetics to join our growing, externally-funded research program. Our overarching goal is to understand the genetic and cellular underpinnings of islet (dys)function and diabetes. We employ innovative (epi)genomic profiling and single cell genomic technologies, mouse models, and CRISPR/Cas9 (epi)genome editing platforms to identify key genes and pathways controlling human islet cell identity and function and to understand how diabetes-associated DNA sequence variants and environmental stimuli/stressors alter these programs to contribute to islet failure in diabetes.
Interested and qualified individuals should submit a current CV, a 1-page (maximum) Statement of Research Interests and Career Goals, and contact information for 3 references at time of application. Our research group is diverse and collaborative, and we seek to produce top notch science and foster the development of outstanding, independent scientists through critical but nurturing mentorship and interdisciplinary, collaborative efforts.
• PhD in genetics, computational biology, molecular/cell biology, or other quantitative science
• Expertise processing, analyzing, and interpreting large genomics datasets, including epigenome (ATAC-seq, ChIP-seq) and transcriptome (RNA-seq) profiles from multiple cell types/tissues is essential. Demonstrated proficiency with integrated genomics analyses preferred. Ideal candidates would also have bench skills that would allow them to generate genomics datasets and functionally test hypotheses generated from analyses.
• Prior research experience in at least two of the following areas: Quantitative genetic or genomic analyses (e.g., eQTL, caQTL, or allelic imbalance), CRISPR/Cas9 (epi)genome editing, single cell genomics, islet or beta cell biology, genomics, iPS/ES culture and directed differentiation
• Track record of productivity supported by first-author publications in peer-reviewed journals
• Outstanding writing and communication skills, with an ability to work both independently and within collaborative teams productively
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,200 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center, a genomic medicine institute in Farmington, Conn., and facilities in Ellsworth, Maine, Sacramento, Calif., and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup.
JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories.
In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
INTEGRITY - Courage and commitment to do what is right
PEOPLE - Inspiring our people to enhance the health of all
ONE TEAM - Unified by our promise to transform medicine and science
EXCELLENCE - Achieving world-class results
INNOVATION - Leading with discovery and creative solutions
STEWARDSHIP - Caring for and enhancing the resources entrusted to us
What do we have to offer?
JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program and an onsite full service cafeteria.
Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.