Working under minimal supervision from Dr. Banchereau, the incumbent is responsible for testing, developing, streamlining, improving and implementing protocols (new or existing) using cutting-edge nucleic acid and library preparation, next generation sequencing (NGS), and associated technologies. In particular, this will apply to generation of Long Read libraries, often following target enrichment. Responsibilities include testing new protocols, preparing biological samples, and constructing NGS libraries. Good knowledge in molecular biology and strong hands-on skills are critical in protocol development and implementation. The applicant will also be experienced in RT-PCR and most importantly, Nanostring, as JAX experience in this fold is limited. Strong interpersonal and written and oral communications skills are required.
The Technologist III is expected to have in depth relevant experience, independent judgment, with minimal supervision required, proficiency in problem solving, and diversity of training. In addition, a Technologist III will be responsible for mentoring and training other members of the lab.
• Isolate DNA and RNA, QC samples, construct and QC NGS libraries, in particular for Long Reads. Troubleshoot to solve problems as they arise. Implement process improvement to improve efficiency and minimize errors. Establish RT-PCR and Nanostring assays.
• Test, develop, and implement new technologies and protocols, including automation where necessary. Document new protocols and write SOPs.
• Aid in acquisition of samples. Maintain project and sample information, protocols, and experimental details through the Laboratory Information Management System (LIMS)
• Train laboratory staff members in new and existing SOPs.
• Level III – Bachelor’s degree in biological or chemical sciences with at least five years of experience in a molecular biology laboratory or Master’s degree with at least three years of experience in a molecular biology laboratory.
• Demonstrated ability to take initiative and identify, prioritize, and plan activities necessary to meet projected goals.
• Good knowledge and hands-on skills on molecular biology is essential, and knowledge of NGS-based genomic research and related technologies is a plus.
• Positive team player
• Exceptional organizational and project management skills, including the ability to plan, schedule, and successfully carry out multiple projects at the same time to successful conclusion with minimal supervision
• Strong attention to experimental detail and process is critically required.
• Working experience in genomics focused laboratory and experience in data management, including laboratory information management systems (LIMS) is desired.
• Excellent written and verbal skills required for efficient communication in scientific details in a diversified environment.
The Jackson Laboratory (JAX, www.jax.org) is a nonprofit biomedical research institute with over 2,000 employees whose mission is to discover precise genomic solutions for human disease and empower the global biomedical community in the shared quest to improve human health. A National Cancer Institute-designated Cancer Center, JAX has a mammalian genetics headquarters in Bar Harbor, Maine, a facility in Sacramento, California, and a genomic medicine facility, The Jackson Laboratory for Genomic Medicine (JAX-GM), in Farmington, Connecticut.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
INTEGRITY - Courage and commitment to do what is right
PEOPLE - Inspiring our people to enhance the health of all
ONE TEAM - Unified by our promise to transform medicine and science
EXCELLENCE - Achieving world-class results
INNOVATION - Leading with discovery and creative solutions
STEWARDSHIP - Caring for and enhancing the resources entrusted to us
What do we have to offer?
JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program, an onsite full service cafeteria, and a fully operational primary care facility available to employees and their families.
Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Learn more about career opportunities at JAX: http://www.jax.org/careers.